Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020644 | 0.94 | HDAC1 (0.58) | HDAC1HDAC2MAPTSMN1; SMN2LMNA | |
| SCHEMBL4020386 | 0.91 | MAPT (0.59) | HDAC1HDAC2MAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL4026426 | 0.83 | MEN1 (0.61) | HDAC1MAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL4020377 | 0.81 | MAPT (0.57) | HDAC1HDAC2MAPTSMN1; SMN2LMNA | |
| SCHEMBL4024552 | 0.80 | NR1H4 (0.53) | HDAC1MAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL16613183 | 0.79 | PDE4D (0.54) | HDAC1HDAC2MAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL4191882 | 0.79 | MAPT (0.53) | HDAC1HDAC2MAPTHSD17B10LMNA | |
| SCHEMBL4653941 | 0.77 | TRPV1 (0.56) | HDAC1HDAC2KDM4EHTTHDAC10 | |
| SCHEMBL4659243 | 0.77 | HDAC3 (0.57) | HDAC1HDAC2MAPTSMN1; SMN2LMNA | |
| SCHEMBL4656274 | 0.76 | NPC1 (0.71) | HDAC1HDAC2MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874722-B1 | HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF | AMOREPACIFIC CORP (KR) | 2015-04-08 | — | — | EP | claimed |
| US-7485750-B2 | Hydroxamic acid derivatives and the preparation method thereof | AMOREPACIFIC CORPORATION (KR) | 2009-02-03 | — | — | US | claimed |
| US-20080242730-A1 | Hydroxamic Acid Derivatives and the Preparation Method Thereof | AMOREPACIFIC CORPORATION (KR) | 2008-10-02 | — | — | US | claimed |
| EP-1874722-A1 | HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF | Amorepacific Corporation (KR) | 2008-01-09 | — | — | EP | claimed |
| WO-2006118380-A1 | HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF | AMOREPACIFIC CORPORATION (KR) | 2006-11-09 | — | — | WO | claimed |
| EP-1874722-B1 | HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF | AMOREPACIFIC CORP (KR) | 2015-04-08 | — | — | EP | disclosed |
| US-7485750-B2 | Hydroxamic acid derivatives and the preparation method thereof | AMOREPACIFIC CORPORATION (KR) | 2009-02-03 | — | — | US | disclosed |
| US-20080242730-A1 | Hydroxamic Acid Derivatives and the Preparation Method Thereof | AMOREPACIFIC CORPORATION (KR) | 2008-10-02 | — | — | US | disclosed |
| EP-1874722-A1 | HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF | Amorepacific Corporation (KR) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006118380-A1 | HYDROXAMIC ACID DERIVATIVES AND THE PREPARATION METHOD THEREOF | AMOREPACIFIC CORPORATION (KR) | 2006-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242730-A1 | Hydroxamic Acid Derivatives and the Preparation Method Thereof | COL14A1, CUTA, COL2A1 | HDAC1 111/4885HDAC2 202/4885MAPT 4518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.