SCHEMBL16613261

SCHEMBL16613261

c1ccc(-c2nc(-n3c4ccccc4c4ccccc43)nc3cscc23)nc1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 6/20 0.40
KDM4E B2RXH2 2/20 0.36
NPC1 O15118 2/20 0.36
TGFBR1 P36897 3/20 0.35
LRRK2 Q5S007 1/20 0.35
NPY5R Q15761 1/20 0.34
METAP1 P53582 4/20 0.34
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16613655 0.89 MCL1 (0.36) MCL1KDM4ENPC1TGFBR1NPY5R
SCHEMBL12014847 0.85 MCL1 (0.47) MCL1KDM4ENPC1METAP1ALDH1A1
SCHEMBL16613250 0.83 MCL1 (0.37) MCL1RAB9A
SCHEMBL16613344 0.81 KDM4E (0.47) KDM4EALDH1A1TSHRHSD17B10
SCHEMBL16613301 0.81 MCL1 (0.41) MCL1KDM4ENPC1TGFBR1LRRK2
SCHEMBL16613252 0.79 KDM4E (0.44) KDM4EALDH1A1TSHRHSD17B10
SCHEMBL16613739 0.79 ADORA1 (0.55) MCL1KDM4ENPC1METAP1
SCHEMBL16613251 0.78 ALDH1A1 (0.35) KDM4EALDH1A1SMN1; SMN2HSD17B10
SCHEMBL21213120 0.78 MCL1 (0.44) MCL1KDM4ENPC1TGFBR1LRRK2
SCHEMBL16613345 0.77 KDM4E (0.37) KDM4EALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015047058-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed