SCHEMBL16613739

SCHEMBL16613739

c1ccc(-c2nc(-n3c4ccccc4c4ccccc43)nc3ccsc23)nc1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 10/20 0.55
ADORA2A P29274 8/20 0.55
MCL1 Q07820 5/20 0.39
POLB P06746 1/20 0.38
METAP1 P53582 2/20 0.37
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
ADORA2B P29275 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16613726 0.82 ADORA1 (0.41) ADORA1ADORA2AMCL1METAP1
SCHEMBL16613601 0.82 KDM4E (0.42) ADORA1ADORA2AKDM4EADORA3
SCHEMBL12014847 0.81 MCL1 (0.47) MCL1POLBMETAP1KDM4ENPC1
SCHEMBL16613460 0.81 KRAS (0.45) ADORA1ADORA2AMCL1KDM4ENPC1
SCHEMBL16613606 0.80 ALDH1A1 (0.40) ADORA1ADORA2APOLBKDM4EADORA3
SCHEMBL16613748 0.79 TUBB4A (0.34) ADORA1ADORA2AADORA3ADORA2B
SCHEMBL16613261 0.79 MCL1 (0.40) MCL1METAP1KDM4ENPC1
SCHEMBL16613738 0.78 PDE4A (0.41) ADORA1ADORA2AKDM4E
SCHEMBL16613737 0.78 MAPT (0.36) ADORA1ADORA2AKDM4E
SCHEMBL16613727 0.78 MAPT (0.36) ADORA1ADORA2AKDM4EADORA3ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015047058-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed