SCHEMBL16613484

SCHEMBL16613484

c1ccc(-c2nc(-n3c4ccccc4c4ccccc43)nc3sccc23)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 2/20 0.42
VCP P55072 1/20 0.41
KDM4E B2RXH2 5/20 0.40
ALDH1A1 P00352 4/20 0.40
HPGD P15428 3/20 0.40
MAPT P10636 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
L3MBTL1 Q9Y468 3/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
LMNA P02545 1/20 0.38
DHODH Q02127 1/20 0.37
ATM Q13315 1/20 0.36
PTGER1 P34995 1/20 0.34
NUDT1 P36639 1/20 0.34
KMT2A Q03164 3/20 0.34
ADORA3 P0DMS8 1/20 0.34
ADORA1 P30542 1/20 0.34
GGPS1 O95749 1/20 0.34
FDPS P14324 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16613485 0.97 DHODH (0.41) ADORA2AVCPKDM4EALDH1A1HPGD
SCHEMBL16613533 0.92 DHODH (0.40) ADORA2AVCPKDM4EALDH1A1HPGD
SCHEMBL16613534 0.91 DHODH (0.39) ADORA2AVCPKDM4EALDH1A1HPGD
SCHEMBL16613657 0.89 ADORA2A (0.48) ADORA2AVCPKDM4EALDH1A1HPGD
SCHEMBL16613531 0.89 ADORA2A (0.39) ADORA2AVCPKDM4EALDH1A1HPGD
SCHEMBL16613566 0.88 KDM4E (0.40) ADORA2AVCPKDM4EALDH1A1HPGD
SCHEMBL16613469 0.88 VCP (0.36) ADORA2AVCPKDM4EALDH1A1HPGD
SCHEMBL16613722 0.87 KDM4E (0.39) ADORA2AVCPKDM4EALDH1A1HPGD
SCHEMBL16613656 0.86 VCP (0.35) ADORA2AVCPALDH1A1DHODH
SCHEMBL16613713 0.86 DHODH (0.36) ADORA2AVCPKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015047058-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed