SCHEMBL16613534

SCHEMBL16613534

c1ccc(-c2cccc(-c3nc(-n4c5ccccc5c5ccccc54)nc4sccc34)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.39
VCP P55072 1/20 0.38
ADORA2A P29274 2/20 0.38
KDM4E B2RXH2 4/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ALDH1A1 P00352 3/20 0.33
HPGD P15428 2/20 0.33
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
L3MBTL1 Q9Y468 3/20 0.32
PTGER1 P34995 1/20 0.32
ATM Q13315 1/20 0.32
LMNA P02545 1/20 0.32
CTSA P10619 1/20 0.31
GGPS1 O95749 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16613533 0.94 DHODH (0.40) DHODHVCPADORA2AKDM4ETSHR
SCHEMBL16613716 0.91 KDM4E (0.38) DHODHVCPADORA2AKDM4ETSHR
SCHEMBL16613485 0.91 DHODH (0.41) DHODHVCPADORA2AKDM4ETSHR
SCHEMBL16613484 0.91 ADORA2A (0.42) DHODHVCPADORA2AKDM4ETSHR
SCHEMBL16613459 0.88 TUBB4A (0.34) DHODHVCPADORA2AKDM4ETSHR
SCHEMBL16613722 0.86 KDM4E (0.39) DHODHVCPADORA2AKDM4ETSHR
SCHEMBL16613566 0.85 KDM4E (0.40) DHODHVCPADORA2AKDM4ETSHR
SCHEMBL16613718 0.84 KDM4E (0.33) DHODHVCPKDM4EL3MBTL1ATM
SCHEMBL16613531 0.84 ADORA2A (0.39) DHODHVCPADORA2AKDM4ETSHR
SCHEMBL16613657 0.84 ADORA2A (0.48) DHODHVCPADORA2AKDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015047058-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed