SCHEMBL16613485

SCHEMBL16613485

c1ccc(-c2ccc(-c3nc(-n4c5ccccc5c5ccccc54)nc4sccc34)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.41
ADORA2A P29274 1/20 0.40
VCP P55072 1/20 0.40
KDM4E B2RXH2 4/20 0.38
ALDH1A1 P00352 4/20 0.38
HPGD P15428 3/20 0.38
MAPT P10636 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 4/20 0.37
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
LMNA P02545 1/20 0.36
ATM Q13315 2/20 0.34
PTGER1 P34995 1/20 0.33
USP1 O94782 1/20 0.33
WDR48 Q8TAF3 1/20 0.33
GGPS1 O95749 1/20 0.33
FDPS P14324 1/20 0.33
POLB P06746 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16613484 0.97 ADORA2A (0.42) DHODHADORA2AVCPKDM4EALDH1A1
SCHEMBL16613533 0.92 DHODH (0.40) DHODHADORA2AVCPKDM4EALDH1A1
SCHEMBL16613534 0.91 DHODH (0.39) DHODHADORA2AVCPKDM4EALDH1A1
SCHEMBL16613722 0.90 KDM4E (0.39) DHODHADORA2AVCPKDM4EALDH1A1
SCHEMBL16613566 0.88 KDM4E (0.40) DHODHADORA2AVCPKDM4EALDH1A1
SCHEMBL16613713 0.88 DHODH (0.36) DHODHADORA2AVCPKDM4EALDH1A1
SCHEMBL16613657 0.87 ADORA2A (0.48) DHODHADORA2AVCPKDM4EALDH1A1
SCHEMBL16613531 0.87 ADORA2A (0.39) DHODHADORA2AVCPKDM4EALDH1A1
SCHEMBL16613656 0.86 VCP (0.35) DHODHADORA2AVCPALDH1A1
SCHEMBL16613716 0.85 KDM4E (0.38) DHODHADORA2AVCPKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015047058-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed