SCHEMBL16613612

SCHEMBL16613612

c1cc(-c2cccc3ccccc23)cc(-c2nc(-n3c4ccccc4c4ccccc43)nc3ccoc23)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CA P42336 2/20 0.35
PIK3CD O00329 1/20 0.35
ALDH1A1 P00352 7/20 0.35
KDM4E B2RXH2 5/20 0.35
MAPT P10636 5/20 0.35
HPGD P15428 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
MAPK1 P28482 2/20 0.35
HSD17B10 Q99714 2/20 0.35
TP53 P04637 1/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
ATM Q13315 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
RORC P51449 1/20 0.35
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16613376 0.92 PIK3CD (0.32) PIK3CAPIK3CDALDH1A1KDM4EMAPT
SCHEMBL16613672 0.91 ENPP1 (0.40) PIK3CAPIK3CDALDH1A1KDM4EMAPT
SCHEMBL16613400 0.90 KDM4E (0.33) PIK3CAPIK3CDALDH1A1KDM4EMAPT
SCHEMBL16613743 0.88 PIK3CA (0.38) PIK3CAPIK3CDALDH1A1KDM4EMAPT
SCHEMBL16613763 0.88 TUBB4A (0.35) PIK3CAPIK3CDALDH1A1KDM4EMAPT
SCHEMBL16613764 0.86 TUBB4A (0.34) PIK3CAPIK3CDALDH1A1KDM4EMAPT
SCHEMBL17408324 0.84 ALDH1A1 (0.46) ALDH1A1KDM4EMAPTHPGDSMN1; SMN2
SCHEMBL16613665 0.84 PIK3CA (0.39) PIK3CAPIK3CDALDH1A1KDM4EMAPT
SCHEMBL16613768 0.84 HPGD (0.43) PIK3CAPIK3CDALDH1A1KDM4EMAPT
SCHEMBL16613669 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015047058-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed