SCHEMBL16613741

SCHEMBL16613741

Clc1nc(-c2cccc3ccccc23)c2cscc2n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.38
KDM4E B2RXH2 4/20 0.38
MAPK11 Q15759 1/20 0.36
MAPK14 Q16539 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP1A2 P05177 2/20 0.35
CYP2A6 P11509 1/20 0.35
MAPT P10636 3/20 0.35
BCHE P06276 1/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PGK1 P00558 1/20 0.34
LMNA P02545 1/20 0.34
PDE5A O76074 1/20 0.34
APP P05067 1/20 0.34
ALOX15 P16050 1/20 0.34
TYMP P19971 1/20 0.33
CYP2C19 P33261 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29572574 0.82 ALDH1A1 (0.54) ALDH1A1KDM4EMEN1KMT2ACYP1A2
SCHEMBL15860268 0.82 ALDH1A1 (0.54) ALDH1A1KDM4EMEN1KMT2ACYP1A2
SCHEMBL16613740 0.78 KDM4E (0.55) ALDH1A1KDM4EMEN1KMT2AMAPT
SCHEMBL16613251 0.76 ALDH1A1 (0.35) ALDH1A1KDM4EMAPK11MAPK14MEN1
SCHEMBL18132488 0.75 MEN1 (0.42) ALDH1A1KDM4EMAPK11MAPK14MEN1
SCHEMBL16613687 0.75 KDM4E (0.54) ALDH1A1KDM4EMEN1KMT2ACYP1A2
SCHEMBL16613359 0.75 ADORA2A (0.56) ALDH1A1KDM4EMEN1KMT2ACYP1A2
SCHEMBL28963940 0.74 ALDH1A1 (0.51) ALDH1A1KDM4EMAPK11MAPK14MEN1
SCHEMBL18132493 0.73 MAPT (0.45) ALDH1A1KDM4EMAPK11MAPK14CYP1A2
SCHEMBL16613407 0.73 RORC (0.40) ALDH1A1KDM4EMAPK11MAPK14MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015047058-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed