SCHEMBL16613407

SCHEMBL16613407

Clc1nc(-c2cccc3ccccc23)c2ccsc2n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.40
RORB Q92753 1/20 0.40
CYP1A2 P05177 3/20 0.35
CYP2A6 P11509 1/20 0.35
ADORA2A P29274 2/20 0.35
ALDH1A1 P00352 5/20 0.35
BCHE P06276 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP2C19 P33261 3/20 0.35
CYP2D6 P10635 2/20 0.35
ADORA1 P30542 1/20 0.34
MAPK11 Q15759 1/20 0.34
MAPK14 Q16539 1/20 0.34
CYP2C9 P11712 1/20 0.34
KDM4E B2RXH2 2/20 0.33
TYMP P19971 1/20 0.33
RAB9A P51151 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16613359 0.78 ADORA2A (0.56) RORCRORBCYP1A2CYP2A6ADORA2A
SCHEMBL16613449 0.78 ALDH1A1 (0.52) ADORA2AALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL29572574 0.76 ALDH1A1 (0.54) CYP1A2CYP2A6ADORA2AALDH1A1BCHE
SCHEMBL15860268 0.76 ALDH1A1 (0.54) CYP1A2CYP2A6ADORA2AALDH1A1BCHE
SCHEMBL16613467 0.75 ALDH1A1 (0.49) CYP1A2ADORA2AALDH1A1MAPTHPGD
SCHEMBL17464083 0.75 DHODH (0.44) RORBCYP1A2ADORA2AALDH1A1MAPT
SCHEMBL17305871 0.74 ADK (0.41) CYP1A2CYP2A6ALDH1A1BCHEMAPT
SCHEMBL18132493 0.73 MAPT (0.45) CYP1A2CYP2A6ALDH1A1BCHEMAPT
SCHEMBL16613741 0.73 ALDH1A1 (0.38) CYP1A2CYP2A6ALDH1A1BCHEMAPT
SCHEMBL16613532 0.72 VCP (0.36) RORCRORBCYP1A2ADORA2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015047058-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed