SCHEMBL16613749

SCHEMBL16613749

c1ccc2c(-c3ccc(-c4nc(-n5c6ccccc6c6ccccc65)nc5ccsc45)cc3)cccc2c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP3 O14638 1/20 0.34
ENPP1 P22413 1/20 0.34
CA12 O43570 3/20 0.33
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
CA9 Q16790 3/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
FLT3 P36888 2/20 0.32
BMX P51813 1/20 0.32
CYP17A1 P05093 1/20 0.32
TUBB4A P04350 1/20 0.32
TUBB P07437 1/20 0.32
TUBA3C P0DPH7 1/20 0.32
TUBA1B P68363 1/20 0.32
TUBA4A P68366 1/20 0.32
TUBB4B P68371 1/20 0.32
TUBB3 Q13509 1/20 0.32
TUBB2A Q13885 1/20 0.32
TUBB8 Q3ZCM7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16613728 0.91 TUBB4A (0.33) CA12CA1CA2CA9FLT3
SCHEMBL16613748 0.90 TUBB4A (0.34) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL16613608 0.88 TUBB4A (0.33) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL16613606 0.87 ALDH1A1 (0.40) KDM4EALDH1A1MAPTHPGDNPSR1
SCHEMBL16613601 0.86 KDM4E (0.42) KDM4EALDH1A1MAPTHPGDNPSR1
SCHEMBL16613727 0.84 MAPT (0.36) KDM4EALDH1A1MAPTHPGDNPSR1
SCHEMBL16613643 0.83
SCHEMBL19271520 0.83 ALDH1A1 (0.48) ENPP3ENPP1CA12CA1CA2
SCHEMBL16613656 0.82 VCP (0.35) ENPP3ENPP1CA12CA1CA2
SCHEMBL16613607 0.81 MAPT (0.36) KDM4EALDH1A1MAPTHPGDNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015047058-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-02 WO disclosed