SCHEMBL16614137

SCHEMBL16614137

c1ccc(N(c2ccc(-c3ccc4ccccc4c3)cc2)c2ccc(C3(c4ccccc4)c4ccccc4-c4c3ccc3c4sc4ccccc43)cc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.32
S1PR4 O95977 1/20 0.31
S1PR5 Q9H228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16614141 0.98 ALOX5 (0.32) ALOX5S1PR4S1PR5
SCHEMBL16614176 0.97 ALOX5 (0.32) ALOX5S1PR4S1PR5
SCHEMBL16614130 0.96 ALOX5 (0.30) ALOX5
SCHEMBL16614129 0.95 ALOX5 (0.33) ALOX5S1PR4S1PR5
SCHEMBL16614116 0.95 ALOX5 (0.32) ALOX5
SCHEMBL16614172 0.93
SCHEMBL16614175 0.92 ALOX5 (0.30) ALOX5
SCHEMBL16614112 0.92 S1PR5 (0.31) ALOX5S1PR4S1PR5
SCHEMBL16614119 0.91 ALOX5 (0.34) ALOX5
SCHEMBL16614146 0.91 ALOX5 (0.34) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917907-B2 Organic electroluminescent device ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-02-27 US disclosed
US-11917907-B2 Organic electroluminescent device ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-02-27 US disclosed
US-20220102633-A1 ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2022-03-31 US disclosed
US-20170213968-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-07-27 US disclosed
US-20170213968-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-07-27 US disclosed
WO-2015046955-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2015-04-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220102633-A1 ORGANIC ELECTROLUMINESCENT DEVICE SOD1, TRPC6, L1CAM ALOX5 1234/4885S1PR4 3140/4885S1PR5 3976/4885
US-11917907-B2 Organic electroluminescent device SOD1, TRPC6, L1CAM ALOX5 1234/4885S1PR4 3140/4885S1PR5 3976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.