Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 7/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | UGCG | Q16739 | 1/20 | 0.41 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23015014 | 0.98 | L3MBTL1 (0.60) | L3MBTL1TDP1IDO1AGXTPYCR1 | |
| SCHEMBL5323565 | 0.98 | L3MBTL1 (0.60) | L3MBTL1TDP1IDO1AGXTPYCR1 | |
| SCHEMBL23014810 | 0.95 | L3MBTL1 (0.57) | L3MBTL1TDP1IDO1AGXTPYCR1 | |
| SCHEMBL25372049 | 0.95 | L3MBTL1 (0.57) | L3MBTL1TDP1IDO1AGXTPYCR1 | |
| SCHEMBL23015037 | 0.95 | L3MBTL1 (0.57) | L3MBTL1TDP1IDO1AGXTPYCR1 | |
| SCHEMBL6530427 | 0.88 | TDP1 (0.50) | L3MBTL1TDP1IDO1AGXTPYCR1 | |
| SCHEMBL26490217 | 0.81 | MIF (0.42) | L3MBTL1TDP1IDO1MAOBAPP | |
| SCHEMBL16614402 | 0.80 | L3MBTL1 (0.54) | L3MBTL1TDP1IDO1AGXTCA1 | |
| SCHEMBL16727736 | 0.80 | L3MBTL1 (0.57) | L3MBTL1TDP1IDO1AGXTCA1 | |
| SCHEMBL26490237 | 0.80 | TDP1 (0.36) | L3MBTL1TDP1MAOBAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160318862-A1 | SYNTHESIS OF DELTA 12-PGJ3 AND RELATED COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY (US) | 2016-11-03 | — | — | US | disclosed |
| WO-2015048268-A1 | SYNTHESIS OF DELTA 12-PGJ3 AND RELATED COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY (US) | 2015-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318862-A1 | SYNTHESIS OF DELTA 12-PGJ3 AND RELATED COMPOUNDS | DGKZ, DGKG, DNAJA3 | L3MBTL1 4273/4885TDP1 3703/4885IDO1 3973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.