Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 9/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26490217 | 0.84 | MIF (0.42) | TDP1L3MBTL1MAOBAPPNAAA | |
| SCHEMBL3376445 | 0.82 | TSHR (0.50) | TDP1L3MBTL1NAAATSHR | |
| SCHEMBL4314778 | 0.81 | TDP1 (0.46) | TDP1L3MBTL1MAOBAPPNAAA | |
| SCHEMBL19608820 | 0.81 | L3MBTL1 (0.50) | TDP1L3MBTL1NAAAALDH1A1CYP3A4 | |
| SCHEMBL1422059 | 0.81 | L3MBTL1 (0.50) | TDP1L3MBTL1NAAAALDH1A1CYP3A4 | |
| SCHEMBL23014897 | 0.81 | L3MBTL1 (0.50) | TDP1L3MBTL1NAAAALDH1A1CYP3A4 | |
| SCHEMBL1421766 | 0.81 | L3MBTL1 (0.50) | TDP1L3MBTL1NAAAALDH1A1CYP3A4 | |
| SCHEMBL16614394 | 0.80 | L3MBTL1 (0.57) | TDP1L3MBTL1MAOBAPP | |
| SCHEMBL5323565 | 0.79 | L3MBTL1 (0.60) | TDP1L3MBTL1MAOBAPP | |
| SCHEMBL5323578 | 0.79 | APP (0.41) | TDP1L3MBTL1APPNAAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230137943-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | THE UNIVERSITY OF CHICAGO | 2023-05-04 | — | — | US | disclosed |
| US-20230137943-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | THE UNIVERSITY OF CHICAGO | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230137943-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | PPIA, S100A4, S100A6 | TDP1 1641/4885L3MBTL1 1481/4885MAOB 3324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.