Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 2/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 6/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16615530 | 0.79 | ALDH1A1 (0.70) | ALDH1A1LMNAMAPTHTTCNR1 | |
| SCHEMBL19074542 | 0.67 | ALDH1A1 (0.82) | ALDH1A1LMNAMAPTHTTCRHBP | |
| SCHEMBL7752354 | 0.67 | ALDH1A1 (0.82) | ALDH1A1LMNAMAPTHTTCRHBP | |
| SCHEMBL16615822 | 0.66 | ALDH1A1 (0.66) | ALDH1A1LMNAMAPTHTTCNR1 | |
| SCHEMBL9138268 | 0.65 | ALDH1A1 (0.68) | ALDH1A1LMNAMAPTHTTCRHBP | |
| SCHEMBL16615850 | 0.65 | SCN3A (0.65) | ALDH1A1LMNAHTTCRHBPCRHR2 | |
| SCHEMBL16615489 | 0.65 | LMNA (0.70) | ALDH1A1LMNAMAPTHTTGPR55 | |
| Acetic Acid SCHEMBL27922009 | 0.65 | ALDH1A1 (0.77) | ALDH1A1LMNAMAPTHTTCRHBP | |
| SCHEMBL16615516 | 0.65 | SMN1; SMN2 (0.65) | ALDH1A1LMNAMAPTHTTCNR1 | |
| SCHEMBL18233524 | 0.64 | ALDH1A1 (0.76) | ALDH1A1LMNAMAPTHTTCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015042685-A1 | INHIBITORS OF POLYNUCLEOTIDE REPEAT-ASSOCIATED RNA FOCI AND USES THEREOF | VALORISATION-RECHERCHE (CA) | 2015-04-02 | — | — | WO | disclosed |