Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 4/20 | 0.37 |
| ▸ | MMP9 | P14780 | 4/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 3/20 | 0.34 |
| ▸ | MMP3 | P08254 | 3/20 | 0.34 |
| ▸ | MMP8 | P22894 | 3/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16615906 | 0.93 | BRAF (0.36) | BRAFMMP1MMP9ADAM17UBE2N | |
| SCHEMBL16615763 | 0.76 | MMP1 (0.36) | MMP1MMP9ADAM17SSTR1MMP2 | |
| SCHEMBL16615623 | 0.75 | SIRT2 (0.42) | BRAFMMP1MMP9ADAM17UBE2N | |
| SCHEMBL16615867 | 0.74 | SIRT2 (0.41) | MMP1MMP9ADAM17UBE2NSMN1; SMN2 | |
| SCHEMBL16615894 | 0.74 | POLB (0.46) | MMP1MMP9ADAM17POLBTDP1 | |
| SCHEMBL16615873 | 0.73 | KEAP1 (0.42) | MMP1MMP9ADAM17UBE2NSMN1; SMN2 | |
| SCHEMBL16615761 | 0.73 | MMP1 (0.41) | MMP1MMP9ADAM17POLBTDP1 | |
| SCHEMBL16691469 | 0.72 | SRC (0.49) | MMP1MMP9POLBTDP1L3MBTL1 | |
| SCHEMBL16615762 | 0.72 | SRC (0.43) | MMP1MMP9SSTR1MMP2MMP3 | |
| SCHEMBL16615920 | 0.72 | MMP1 (0.38) | BRAFMMP1MMP9ADAM17POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015044900-A1 | THERAPEUTIC IMMUNOMODULATING COMPOUNDS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2015-04-02 | — | — | WO | disclosed |