Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 5/20 | 0.39 |
| ▸ | MMP1 | P03956 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 6/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | SIRT7 | Q9NRC8 | 3/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16615916 | 0.89 | MMP9 (0.43) | KEAP1MMP1MMP9ADAM17SIRT2 | |
| SCHEMBL16615873 | 0.86 | KEAP1 (0.42) | KEAP1MMP1MMP9ADAM17SIRT2 | |
| SCHEMBL16615907 | 0.84 | MMP1 (0.41) | KEAP1MMP1MMP9ADAM17SIRT2 | |
| SCHEMBL16615604 | 0.82 | SIRT2 (0.40) | KEAP1MMP1MMP9ADAM17SIRT2 | |
| SCHEMBL16615892 | 0.77 | MMP1 (0.41) | KEAP1MMP1MMP9ADAM17SIRT2 | |
| SCHEMBL16615902 | 0.77 | MMP1 (0.42) | MMP1MMP9ADAM17SIRT2SIRT1 | |
| SCHEMBL16615913 | 0.76 | MMP9 (0.42) | KEAP1MMP1MMP9ADAM17SIRT2 | |
| SCHEMBL16615622 | 0.74 | MMP1 (0.41) | KEAP1MMP1MMP9ADAM17SIRT2 | |
| SCHEMBL16615760 | 0.73 | MMP1 (0.40) | KEAP1MMP1MMP9ADAM17SIRT2 | |
| SCHEMBL16615648 | 0.72 | MMP9 (0.39) | KEAP1MMP1MMP9ADAM17SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015044900-A1 | THERAPEUTIC IMMUNOMODULATING COMPOUNDS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2015-04-02 | — | — | WO | disclosed |