Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 4/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.45 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.45 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16616629 | 0.81 | KCNQ2 (0.57) | KCNQ3KCNQ2KCNQ4KCNQ5KDM4E | |
| SCHEMBL16616466 | 0.81 | KCNQ2 (0.46) | KCNQ3KCNQ2KCNQ4KCNQ5KDM4E | |
| SCHEMBL15347739 | 0.75 | KCNQ2 (0.60) | KCNQ3KCNQ2KCNQ4KCNQ5KDM4E | |
| SCHEMBL16616570 | 0.74 | KCNQ3 (0.51) | KCNQ3KCNQ2KCNQ4KCNQ5KDM4E | |
| SCHEMBL4058596 | 0.74 | KCNQ3 (0.56) | KCNQ3KCNQ2KDM4EMAPTLMNA | |
| SCHEMBL16625701 | 0.73 | KCNQ3 (0.46) | KCNQ3KCNQ2KCNQ4KCNQ5KDM4E | |
| SCHEMBL16616890 | 0.73 | KCNQ2 (0.47) | KCNQ3KCNQ2KCNQ4KCNQ5KDM4E | |
| SCHEMBL15357204 | 0.72 | KCNQ2 (0.81) | KCNQ3KCNQ2KCNQ4KCNQ5KDM4E | |
| SCHEMBL16616405 | 0.72 | KCNQ3 (0.43) | KCNQ3KCNQ2KCNQ4KCNQ5KDM4E | |
| SCHEMBL16616403 | 0.72 | KCNQ3 (0.43) | KCNQ3KCNQ2KCNQ4KCNQ5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556114-B2 | Fluorinated 2-amino-4-(benzylamino)phenylcarbamate derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-01-31 | — | — | US | disclosed |
| US-20150098902-A1 | Fluorinated 2-Amino-4-(Benzylamino)Phenylcarbamate Derivatives | SCIFLUOR LIFE SCIENCES, INC. | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150098902-A1 | Fluorinated 2-Amino-4-(Benzylamino)Phenylcarbamate Derivatives | FAAH, CACNA1B, FAAH2 | KCNQ3 48/4885KCNQ2 30/4885KCNQ4 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.