⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL661575 | 1.00 | HSD17B10 (0.58) | — | |
| SCHEMBL6473560 | 1.00 | HSD17B10 (0.58) | — | |
| SCHEMBL893723 | 0.97 | HSD17B10 (0.56) | — | |
| SCHEMBL21454626 | 0.97 | HSD17B10 (0.56) | — | |
| SCHEMBL1065178 | 0.97 | HSD17B10 (0.56) | — | |
| Hydrochloric Acid SCHEMBL18980658 | 0.97 | — | — | |
| SCHEMBL17512849 | 0.97 | HSD17B10 (0.56) | — | |
| SCHEMBL321552 | 0.97 | HSD17B10 (0.56) | — | |
| SCHEMBL454245 | 0.97 | HSD17B10 (0.56) | — | |
| SCHEMBL336249 | 0.97 | HSD17B10 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103797011-A | Compounds and compositions as c-Kit kinase inhibitors | IRM LLC | 2014-05-14 | — | — | CN | claimed |
| CN-102256977-A | Purine compounds | LILLY CO ELI | 2011-11-23 | — | — | CN | claimed |
| EP-0114706-B1 | 2-ACETIDINYLACETIC ACID,ITS PREPARATION,COMPOSITIONS CONTAINING IT,AND METHOD OF STERILISING THE ANTHERS OF A PLANT | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-09-09 | — | — | EP | claimed |
| EP-0114706-A1 | 2-Acetidinylacetic acid,its preparation,compositions containing it,and method of sterilising the anthers of a plant | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-08-01 | — | — | EP | claimed |
| JP-54046797-A | — | — | None | — | — | JP | disclosed |
| WO-2024220399-A1 | PYRAZOLOTRIAZINECARBONITRILES USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-10-24 | — | — | WO | disclosed |
| CN-114685531-B | Tetrafused ring compound, and pharmaceutical composition and application thereof | 武汉誉祥医药科技有限公司 | 2024-10-22 | — | — | CN | disclosed |
| US-20240025922-A1 | TETRAHYDROPYRIDO[3,4-d]PYRIMIDINES AS HPK1 INHIBITORS | MERCK HEALTHCARE KGAA (DE) | 2024-01-25 | — | — | US | disclosed |
| US-20240025922-A1 | TETRAHYDROPYRIDO[3,4-d]PYRIMIDINES AS HPK1 INHIBITORS | MERCK HEALTHCARE KGAA (DE) | 2024-01-25 | — | — | US | disclosed |
| WO-2023235380-A1 | MACROLIDES FOR TREATING GENETIC DISEASES | ZIKANI THERAPEUTICS, INC. (US) | 2023-12-07 | — | — | WO | disclosed |
| CN-115956080-A | Bicyclic compounds, compositions containing them and their use | 贝达药业股份有限公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-115867545-A | Antiviral 1,3 dioxoindene compounds | 诺华股份有限公司 | 2023-03-28 | — | — | CN | disclosed |
| US-4440683-A | Cyclization to form cephem ring and azetidinone intermediates therefor | SHIONOGI & CO., LTD. (JP) | 1984-04-03 | — | — | US | disclosed |
| US-4346218-A | DECYCLIZATION OF AN AZETIDINOTHIAZOLINE | SHIONOGI & CO., LTD. (JP) | 1982-08-24 | — | — | US | disclosed |
| US-4332722-A | BICYCLIC AZETIDINOTHIAZOLINES | SHIONOGI & CO., LTD. (JP) | 1982-06-01 | — | — | US | disclosed |
| US-4160085-A | Cyclization to form cephem ring and intermediates therefor | SHIONOGI & CO., LTD. (JP) | 1979-07-03 | — | — | US | disclosed |
| US-4158004-A | Process for antibiotic FR 1923 and related compounds | ELI LILLY AND COMPANY (US) | 1979-06-12 | — | — | US | disclosed |
| JP-S5446797-A | PREPARATION OF AZAOXABICYCLOHEPTANE | SANKYO CO LTD | 1979-04-12 | — | — | JP | disclosed |
| US-4115383-A | Alkoxycarbonyl-ethylthio-azetidinones and process for their preparation | ELI LILLY AND COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4079181-A | INTERMEDIATES FOR 3-HYDROXY-3-CEPHEM COMPOUNDS | SHIONOGI & CO., LTD. (JA) | 1978-03-14 | — | — | US | disclosed |