Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1661688 | 1.00 | — | — | |
| SCHEMBL6473560 | 1.00 | HSD17B10 (0.58) | HSD17B10GAAALDH1A1CYP1A2MAPK1 | |
| SCHEMBL893723 | 0.97 | HSD17B10 (0.56) | HSD17B10GAAALDH1A1CYP1A2MAPK1 | |
| SCHEMBL21454626 | 0.97 | HSD17B10 (0.56) | HSD17B10GAAALDH1A1CYP1A2MAPK1 | |
| SCHEMBL1065178 | 0.97 | HSD17B10 (0.56) | HSD17B10GAAALDH1A1CYP1A2MAPK1 | |
| Hydrochloric Acid SCHEMBL18980658 | 0.97 | — | — | |
| SCHEMBL17512849 | 0.97 | HSD17B10 (0.56) | HSD17B10GAAALDH1A1CYP1A2MAPK1 | |
| SCHEMBL321552 | 0.97 | HSD17B10 (0.56) | HSD17B10GAAALDH1A1CYP1A2MAPK1 | |
| SCHEMBL454245 | 0.97 | HSD17B10 (0.56) | HSD17B10GAAALDH1A1CYP1A2MAPK1 | |
| SCHEMBL336249 | 0.97 | HSD17B10 (0.56) | HSD17B10GAAALDH1A1CYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10227376-B2 | Radiolabeled cationic steroid antimicrobials and diagnostic methods | BRIGHAM YOUNG UNIVERSITY (US) | 2019-03-12 | — | — | US | claimed |
| US-20160052959-A1 | RADIOLABELED CATIONIC STEROID ANTIMICROBIALS AND DIAGNOSTIC METHODS | BRIGHAM YOUNG UNIVERSITY (US) | 2016-02-25 | — | — | US | claimed |
| EP-2394639-B1 | Hyperthermic technologies and therapeutic uses thereof | UNIV WAKE FOREST HEALTH SCIENCES (US) | 2014-07-30 | — | — | EP | claimed |
| US-20130142735-A1 | In Vivo Mitochondrial Labeling Using Positively-CHarged Nitroxide Enhanced and Gadolinum Chelate Enhanced Magnetic Resonance Imaging | KALYANARAMAN BALARAMAN (US) | 2013-06-06 | — | — | US | claimed |
| US-20100316566-A1 | RADIOLABELED HEDGEHOG DERIVATIVES FOR IMAGING AND THERAPY | RADIOMEDIX INC. (US) | 2010-12-16 | — | — | US | claimed |
| WO-2009108868-A2 | RADIOLABELED HEDGEHOG DERIVATIVES FOR IMAGING AND THERAPY | RADIOMEDIX INC. (US) | 2009-09-03 | — | — | WO | claimed |
| US-20090214437-A1 | In Vivo Mitochondrial Labeling Using Positively-Charged Nitroxide Enhanced and Gadolinium Chelate Enhanced Magnetic Resonance Imaging | MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION (US) | 2009-08-27 | — | — | US | claimed |
| US-20050026929-A1 | Novel phenyl derivatives as inducers of apoptosis | AXYS PHARMACEUTICALS, INC. (US) | 2005-02-03 | — | — | US | claimed |
| US-6806363-B1 | DRUGS FOR DIAGNOSIS/THERAPY; RADIONUCLIDE-BASED TUMOR IMAGING | MAYO FOUNDATION FOR MEDICAL EDUCATION & RESEARCH | 2004-10-19 | — | — | US | claimed |
| US-6613305-B1 | Cobalamin or derivative complexed with a chelating group associated with a radioactive metal for tumor and organ imaging | MAYO FOUNDATION FOR MEDICAL EDUCATION & RESEARCH | 2003-09-02 | — | — | US | claimed |
| US-10227376-B2 | Radiolabeled cationic steroid antimicrobials and diagnostic methods | BRIGHAM YOUNG UNIVERSITY (US) | 2019-03-12 | — | — | US | disclosed |
| US-20170096472-A1 | ALBUMIN FUSION PROTEINS | HUMAN GENOME SCIENCES, INC. | 2017-04-06 | — | — | US | disclosed |
| US-20160152687-A1 | ALBUMIN FUSION PROTEINS | HUMAN GENOME SCIENCES, INC. | 2016-06-02 | — | — | US | disclosed |
| US-9296809-B2 | Albumin fusion proteins | HUMAN GENOME SCIENCES, INC. (US) | 2016-03-29 | — | — | US | disclosed |
| EP-2990417-A1 | ALBUMIN INSULIN FUSION PROTEIN | Human Genome Sciences, Inc. (US) | 2016-03-02 | — | — | EP | disclosed |
| EP-0883627-A1 | RADIONUCLIDE LABELING OF VITAMIN B12 AND COENZYMES THEREOF | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1998-12-16 | — | — | EP | disclosed |
| US-5739313-A | FOR IN VIVO IMAGING OF ORGANS AND TUMORS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1998-04-14 | — | — | US | disclosed |
| WO-1997018231-A1 | RADIONUCLIDE LABELING OF VITAMIN B12 AND COENZYMES THEREOF | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1997-05-22 | — | — | WO | disclosed |
| US-4639365-A | Gadolinium chelates as NMR contrast agents | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1987-01-27 | — | — | US | disclosed |
| US-4639365-A | Gadolinium chelates as NMR contrast agents | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1987-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130142735-A1 | In Vivo Mitochondrial Labeling Using Positively-CHarged Nitroxide Enhanced and Gadolinum Chelate Enhanced Magnetic Resonance Imaging | NME4, GLS, CS | HSD17B10 3731/4885GAA 259/4885ALDH1A1 4646/4885 |
| US-20050026929-A1 | Novel phenyl derivatives as inducers of apoptosis | BAX, BAD, CASP3 | HSD17B10 1592/4885GAA 1718/4885ALDH1A1 1781/4885 |
| US-20160152687-A1 | ALBUMIN FUSION PROTEINS | ALB, FABP1, HDGF | HSD17B10 3544/4885GAA 334/4885ALDH1A1 2350/4885 |
| US-20100316566-A1 | RADIOLABELED HEDGEHOG DERIVATIVES FOR IMAGING AND THERAPY | SHH, GLI1, SMO | HSD17B10 2915/4885GAA 2066/4885ALDH1A1 825/4885 |
| US-20090214437-A1 | In Vivo Mitochondrial Labeling Using Positively-Charged Nitroxide Enhanced and Gadolinium Chelate Enhanced Magnetic Resonance Imaging | NME4, NLN, CS | HSD17B10 2984/4885GAA 416/4885ALDH1A1 4716/4885 |
| US-10227376-B2 | Radiolabeled cationic steroid antimicrobials and diagnostic methods | SERPINA6, CALCA, MYADM | HSD17B10 1917/4885GAA 2669/4885ALDH1A1 4826/4885 |
| US-20160052959-A1 | RADIOLABELED CATIONIC STEROID ANTIMICROBIALS AND DIAGNOSTIC METHODS | SERPINA6, CALCA, CALCB | HSD17B10 1937/4885GAA 2661/4885ALDH1A1 4826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.