SCHEMBL336249

SCHEMBL336249

O=C(O)CN1CCCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1

nearest known ligand 0.83

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.56
GAA P10253 1/20 0.46
ALDH1A1 P00352 4/20 0.43
SLC6A9 P48067 1/20 0.43
CYP1A2 P05177 1/20 0.43
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
SIGMAR1 Q99720 2/20 0.39
S1PR1 P21453 1/20 0.38
HTT P42858 1/20 0.38
ITGB3 P05106 1/20 0.37
ITGA2B P08514 1/20 0.37
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL893723 1.00 HSD17B10 (0.56) HSD17B10GAAALDH1A1SLC6A9CYP1A2
SCHEMBL3504659 1.00 HSD17B10 (0.56) HSD17B10GAAALDH1A1SLC6A9CYP1A2
SCHEMBL1065178 1.00 HSD17B10 (0.56) HSD17B10GAAALDH1A1SLC6A9CYP1A2
SCHEMBL21454626 1.00 HSD17B10 (0.56) HSD17B10GAAALDH1A1SLC6A9CYP1A2
SCHEMBL454245 1.00 HSD17B10 (0.56) HSD17B10GAAALDH1A1SLC6A9CYP1A2
SCHEMBL321552 1.00 HSD17B10 (0.56) HSD17B10GAAALDH1A1SLC6A9CYP1A2
SCHEMBL17512849 1.00 HSD17B10 (0.56) HSD17B10GAAALDH1A1SLC6A9CYP1A2
SCHEMBL21320722 0.97 HSD17B10 (0.54) HSD17B10GAAALDH1A1SLC6A9CYP1A2
SCHEMBL1661688 0.97
SCHEMBL661575 0.97 HSD17B10 (0.58) HSD17B10GAAALDH1A1SLC6A9CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 555 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099626-A1 METHODS AND SYSTEMS FOR MANUFACTURING RADIOPHARMACEUTICALS NOVARTIS AG (CH) 2026-05-15 WO claimed
CN-122005879-A Modified GRPR antagonist peptides for cancer imaging and treatment 慕尼黑工业大学 2026-05-12 CN claimed
US-20260069726-A1 ZWITTERIONIC COMPOUNDS AND USES THEREOF UNIV SASKATCHEWAN (CA) 2026-03-12 US claimed
EP-4642489-A1 CONJUGATE AND USES THEREOF Full-Life Technologies HK Limited (HK) 2025-11-05 EP claimed
WO-2025202114-A1 RADIOSENSITISING PEPTIDE COMPLEX GCS INSTITUT DE CANCEROLOGIE STRASBOURG EUROPE (FR) 2025-10-02 WO claimed
US-20250288702-A1 LABELING PRECURSORS WITH SQUARIC ACID COUPLING Telix Pharmaceuticals Limited (AU) 2025-09-18 US claimed
WO-2025125621-A1 CANCER-ASSOCIATED PROTEIN-TARGETED STRONG OR COVALENTLY BINDING PRECURSOR COMPOUNDS AND RADIOTRACERS RADIOVAXX GMBH (DE) 2025-06-19 WO claimed
WO-2024212001-A9 2,4-DIHYROXY-5-ISOPROPYLPHENYL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF EFFECTIVE AS EXTRACELLULAR HSP90, (EHSP90)-TARGETED RADIOPHARMACEUTICALS USEFUL IN THE TREATMENT OF CANCER Fusion Pharmaceuticals Inc. (CA) 2025-06-19 WO claimed
US-20250177581-A1 NTSR1-TARGETED RADIOPHARMACEUTICALS AND DNA DAMAGE RESPONSE INHIBITOR COMBINATION THERAPY FUSION PHARMACEUTICALS INC (CA) 2025-06-05 US claimed
US-20250163239-A1 Metal-Labeled Polymer Microbeads with Control Over Labeling Level THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2025-05-22 US claimed
US-20140234211-A1 SUPRAMOLECULAR AGGREGATES CONTAINING AMPHIPHILIC MONOMERS, CHELATING AGENTS AND PEPTIDES FOR USE FOR DRUG DELIVERY AND AS CONTRAST AGENTS INVECTORS S.R.L. (IT) 2014-08-21 US claimed
US-20130302243-A1 RADIOLABELED NANOSYSTEM, PROCESS FOR THE PREPARATION THEREOF AND ITS USE BBS NANOMEDICINA ZRT. (HU) 2013-11-14 US claimed
EP-1257575-B1 RADIOLABELED VASOACTIVE INTESTINAL PEPTIDE ANALOGS FOR DIAGNOSIS AND RADIOTHERAPY DABUR RES FOUNDATION (IN) 2007-02-28 EP claimed
US-6706252-B1 Method of treating disease with radioisotopes conjugated to bioactive substances RX/IBR CORPORATION 2004-03-16 US claimed
US-6608174-B1 Of given amino acid sequence; radionuclides; use as scintigraphic imaging agents for visualization of tumors and metastasis DABUR RESEARCH FOUNDATION (IN) 2003-08-19 US claimed
EP-1257575-A1 RADIOLABELED VASOACTIVE INTESTINAL PEPTIDE ANALOGS FOR DIAGNOSIS AND RADIOTHERAPY Dabur Research Foundation (IN) 2002-11-20 EP claimed
WO-2001060863-A1 RADIOLABELED VASOACTIVE INTESTINAL PEPTIDE ANALOGS FOR DIAGNOSIS AND RADIOTHERAPY DABUR RESEARCH FOUNDATION (IN) 2001-08-23 WO claimed
US-5776894-A Chelated somatostatin peptides and complexes thereof, pharmaceutical compositions containing them and their use in treating tumors NOVARTIS AG (CH) 1998-07-07 US claimed
US-5753627-A Use of certain complexed somatostatin peptides for the invivo imaging of somatostatin receptor-positive tumors and metastasis NOVARTIS AG (CH) 1998-05-19 US claimed
EP-0498771-A2 MSH peptide derivatives SANDOZ LTD. (CH) 1992-08-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250177581-A1 NTSR1-TARGETED RADIOPHARMACEUTICALS AND DNA DAMAGE RESPONSE INHIBITOR COMBINATION THERAPY NTSR1, NTSR2, NPSR1 HSD17B10 4478/4885GAA 2524/4885ALDH1A1 3190/4885
US-20140234211-A1 SUPRAMOLECULAR AGGREGATES CONTAINING AMPHIPHILIC MONOMERS, CHELATING AGENTS AND PEPTIDES FOR USE FOR DRUG DELIVERY AND AS CONTRAST AGENTS GRPR, BRS3, BID HSD17B10 4833/4885GAA 3593/4885ALDH1A1 4807/4885
US-20260069726-A1 ZWITTERIONIC COMPOUNDS AND USES THEREOF CA13, SLCO2B1, SLCO2A1 HSD17B10 2357/4885GAA 2122/4885ALDH1A1 1600/4885
US-20250288702-A1 LABELING PRECURSORS WITH SQUARIC ACID COUPLING SCLY, SRRT, CS HSD17B10 2187/4885GAA 32/4885ALDH1A1 1343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.