Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9271782 | 0.85 | CYP19A1 (0.43) | CYP2D6TP53MAPTGRM5GRM1 | |
| SCHEMBL8353444 | 0.77 | ALDH1A1 (0.60) | CYP2D6ALDH1A1MAPTHPGDSLC22A1 | |
| SCHEMBL3918548 | 0.76 | HTR2A (0.54) | TP53MEN1ALDH1A1MAPTHPGD | |
| SCHEMBL14098113 | 0.74 | CYP2D6 (0.39) | CYP2D6MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL13319990 | 0.74 | CYP2D6 (0.46) | CYP2D6TP53MEN1ALDH1A1MAPT | |
| SCHEMBL7001557 | 0.74 | HTR2A (0.58) | CYP2D6TP53GRM5GRM1LMNA | |
| SCHEMBL4664795 | 0.72 | GRM1 (0.49) | CYP2D6TP53MEN1KMT2AHSD17B10 | |
| SCHEMBL79265 | 0.71 | MAOA (0.48) | MEN1MAPTHTTKMT2AGRM5 | |
| SCHEMBL14415670 | 0.71 | HTR2A (0.55) | CYP2D6TP53GRM5GRM1LMNA | |
| SCHEMBL31613809 | 0.71 | GSK3B (0.56) | MAPTSLC22A1PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567277-B2 | Reagent for enhancing generation of chemical species | TOYO GOSEI CO., LTD. (JP) | 2017-02-14 | — | — | US | disclosed |
| US-9567277-B2 | Reagent for enhancing generation of chemical species | TOYO GOSEI CO., LTD. (JP) | 2017-02-14 | — | — | US | disclosed |
| US-9567277-B2 | Reagent for enhancing generation of chemical species | TOYO GOSEI CO., LTD. (JP) | 2017-02-14 | — | — | US | disclosed |
| US-20150099893-A1 | REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES | OSAKA UNIVERSITY (JP) | 2015-04-09 | — | — | US | disclosed |
| US-20150099893-A1 | REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES | OSAKA UNIVERSITY (JP) | 2015-04-09 | — | — | US | disclosed |
| US-20150099893-A1 | REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES | OSAKA UNIVERSITY (JP) | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099893-A1 | REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES | PPOX, CYBB, CBR3 | CYP2D6 1970/4885TP53 2340/4885MEN1 1842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.