Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6931929 | 0.85 | CASR (0.49) | CASRMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL17075263 | 0.77 | CASR (0.46) | CASRALDH1A1L3MBTL1KDM4ECYP2C19 | |
| SCHEMBL7158465 | 0.75 | CASR (0.40) | CASRALDH1A1L3MBTL1KDM4ECYP2C19 | |
| SCHEMBL27978773 | 0.74 | CASR (0.41) | CASRMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL6574077 | 0.72 | GABBR2 (0.42) | CASRCYP2C19CYP2D6NPSR1SMN1; SMN2 | |
| SCHEMBL1906076 | 0.72 | MEN1 (0.44) | CASRMEN1KMT2AALDH1A1POLB | |
| SCHEMBL20241505 | 0.72 | CASR (0.37) | CASRMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11434362 | 0.72 | CASR (0.40) | CASRMEN1KMT2AALDH1A1L3MBTL1 | |
| Glycerin SCHEMBL6931931 | 0.71 | CASR (0.38) | CASRMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL28250335 | 0.71 | POLB (0.38) | CASRMEN1KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9782609-B2 | Dihydroxyalkyl substituted polygalactomannan, and methods for producing and using the same | HERCULES LLC (US) | 2017-10-10 | — | — | US | claimed |
| EP-3055318-A2 | DIHYDROXYALKYL SUBSTITUTED POLYGALACTOMANNAN, AND METHODS FOR PRODUCING AND USING THE SAME | Hercules Incorporated (US) | 2016-08-17 | — | — | EP | claimed |
| WO-2015054026-A2 | DIHYDROXYALKYL SUBSTITUTED POLYGALACTOMANNAN, AND METHODS FOR PRODUCING AND USING THE SAME | HERCULES INCORPORATED (US) | 2015-04-16 | — | — | WO | claimed |
| US-20150098921-A1 | DIHYDROXYALKYL SUBSTITUTED POLYGALACTOMANNAN, AND METHODS FOR PRODUCING AND USING THE SAME | ISP INVESTMENTS LLC | 2015-04-09 | — | — | US | claimed |
| CN-105793273-B | Dihydroxyalkyl-substituted polygalactomannans and methods of making and using same | 赫尔克里士公司 | 2020-02-28 | — | — | CN | disclosed |
| US-9782609-B2 | Dihydroxyalkyl substituted polygalactomannan, and methods for producing and using the same | HERCULES LLC (US) | 2017-10-10 | — | — | US | disclosed |
| EP-3055318-A2 | DIHYDROXYALKYL SUBSTITUTED POLYGALACTOMANNAN, AND METHODS FOR PRODUCING AND USING THE SAME | Hercules Incorporated (US) | 2016-08-17 | — | — | EP | disclosed |
| WO-2015054026-A2 | DIHYDROXYALKYL SUBSTITUTED POLYGALACTOMANNAN, AND METHODS FOR PRODUCING AND USING THE SAME | HERCULES INCORPORATED (US) | 2015-04-16 | — | — | WO | disclosed |
| US-20150098921-A1 | DIHYDROXYALKYL SUBSTITUTED POLYGALACTOMANNAN, AND METHODS FOR PRODUCING AND USING THE SAME | ISP INVESTMENTS LLC | 2015-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150098921-A1 | DIHYDROXYALKYL SUBSTITUTED POLYGALACTOMANNAN, AND METHODS FOR PRODUCING AND USING THE SAME | IDUA, DDOST, ALG1 | CASR 4717/4885MEN1 3058/4885KMT2A 1918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.