Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6931929 | 0.85 | CASR (0.49) | CASRALDH1A1CYP2C19GSRLMNA | |
| SCHEMBL7158465 | 0.79 | CASR (0.40) | CASRALDH1A1CYP2C19GSRTRPA1 | |
| SCHEMBL16617907 | 0.77 | CASR (0.48) | CASRALDH1A1CYP2C19LMNAKDM4E | |
| SCHEMBL27978773 | 0.77 | CASR (0.41) | CASRALDH1A1CYP2C19LMNAKDM4E | |
| SCHEMBL7778374 | 0.77 | CASR (0.37) | CASRALDH1A1CYP2C19TRPA1LMNA | |
| Glycerin SCHEMBL6931931 | 0.75 | CASR (0.38) | CASRALDH1A1CYP2C19GSRTRPA1 | |
| SCHEMBL6574077 | 0.72 | GABBR2 (0.42) | CASRCYP2C19CYP1A2CYP2D6PKM | |
| SCHEMBL1906076 | 0.72 | MEN1 (0.44) | CASRALDH1A1CYP2C19KDM4ECYP2D6 | |
| SCHEMBL20241505 | 0.72 | CASR (0.37) | CASRALDH1A1CYP2C19LMNAKDM4E | |
| SCHEMBL11434362 | 0.72 | CASR (0.40) | CASRALDH1A1CYP2C19LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10966909-B2 | Resin composites for use in dental preventive and restorative applications | ADA FOUNDATION (US) | 2021-04-06 | — | — | US | disclosed |
| US-20200297587-A1 | RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | ADA FOUNDATION (US) | 2020-09-24 | — | — | US | disclosed |
| US-10675224-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | ADA FOUNDATION (US) | 2020-06-09 | — | — | US | disclosed |
| US-20190209438-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | ADA FOUNDATION (US) | 2019-07-11 | — | — | US | disclosed |
| US-10231906-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | ADA FOUNDATION (US) | 2019-03-19 | — | — | US | disclosed |
| EP-3270870-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL APPLICATIONS | ADA FOUNDATION (US) | 2018-01-24 | — | — | EP | disclosed |
| US-20170049666-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | ADA FOUND (US) | 2017-02-23 | — | — | US | disclosed |
| US-9572753-B2 | Enzymatically and hydrolytically stable resins, resin monomers, and resin composites for use in dental preventive and restorative applications | ADA FOUNDATION (US) | 2017-02-21 | — | — | US | disclosed |
| WO-2016160299-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL APPLICATIONS | ADA FOUNDATION (US) | 2016-10-06 | — | — | WO | disclosed |
| US-20150257986-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | ADA FOUNDATION | 2015-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190209438-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | GGH, DNPH1, BCHE | CASR 3577/4885ALDH1A1 321/4885CYP2C19 621/4885 |
| US-10675224-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | GGH, DNPH1, BCHE | CASR 3577/4885ALDH1A1 321/4885CYP2C19 621/4885 |
| US-10966909-B2 | Resin composites for use in dental preventive and restorative applications | SUV39H2, CBX3, SUV39H1 | CASR 3168/4885ALDH1A1 1332/4885CYP2C19 2145/4885 |
| US-20170049666-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE DENTAL PREVENTIVE AND RESTORATIVE SYSTEMS | GGH, DNPH1, BCHE | CASR 3577/4885ALDH1A1 321/4885CYP2C19 621/4885 |
| US-20200297587-A1 | RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | SUV39H2, CBX3, SUV39H1 | CASR 3168/4885ALDH1A1 1332/4885CYP2C19 2145/4885 |
| US-20150257986-A1 | ENZYMATICALLY AND HYDROLYTICALLY STABLE RESINS, RESIN MONOMERS, AND RESIN COMPOSITES FOR USE IN DENTAL PREVENTIVE AND RESTORATIVE APPLICATIONS | ESD, JMJD6, DNPH1 | CASR 3421/4885ALDH1A1 377/4885CYP2C19 821/4885 |
| US-10231906-B2 | Enzymatically and hydrolytically stable dental preventive and restorative systems | GGH, DNPH1, BCHE | CASR 3577/4885ALDH1A1 321/4885CYP2C19 621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.