Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20364486 | 0.77 | TDP1 (0.44) | LMNAF2TSHRALDH1A1ATM | |
| SCHEMBL27630004 | 0.76 | CES1 (0.44) | CES1LMNAF2TSHRALDH1A1 | |
| SCHEMBL7146887 | 0.75 | TDP1 (0.50) | CES1LMNAF2TSHRALDH1A1 | |
| SCHEMBL31538079 | 0.73 | CES1 (0.41) | CES1LMNAF2TSHRALDH1A1 | |
| SCHEMBL219676 | 0.73 | LMNA (0.56) | CES1LMNAF2TSHRALDH1A1 | |
| SCHEMBL21841083 | 0.72 | ALDH1A1 (0.47) | CES1LMNATSHRALDH1A1ATM | |
| SCHEMBL27852696 | 0.72 | CES1 (0.39) | CES1LMNATSHRALDH1A1CES2 | |
| SCHEMBL214249 | 0.72 | LMNA (0.42) | CES1LMNAF2TSHRALDH1A1 | |
| SCHEMBL28123902 | 0.71 | LMNA (0.54) | CES1LMNAF2TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL6620902 | 0.71 | LMNA (0.54) | CES1LMNAF2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3128841-A1 | USE OF SUBSTITUTED OXO TETRAHYDROQUINOLINE SULFONAMIDES OR SALTS THEREOF FOR RAISING STRESS TOLERANCE OF PLANTS | Bayer CropScience Aktiengesellschaft (DE) | 2017-02-15 | — | — | EP | disclosed |
| EP-3051946-A1 | USE OF SUBSTITUTED DIHYDRO-OXINDOLYL SULFONAMIDES, OR THE SALTS THEREOF, FOR INCREASING THE STRESS TOLERANCE OF PLANTS | Bayer CropScience Aktiengesellschaft (DE) | 2016-08-10 | — | — | EP | disclosed |
| CN-102459202-B | As the inhibitor isoxazoline of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS, INC. (US) | 2015-11-25 | — | — | CN | disclosed |
| WO-2015155154-A1 | USE OF SUBSTITUTED OXO TETRAHYDROQUINOLINE SULFONAMIDES OR SALTS THEREOF FOR RAISING STRESS TOLERANCE OF PLANTS | BAYER CROPSCIENCE AG (DE) | 2015-10-15 | — | — | WO | disclosed |
| WO-2015049351-A1 | USE OF SUBSTITUTED DIHYDRO-OXINDOLYL SULFONAMIDES, OR THE SALTS THEREOF, FOR INCREASING THE STRESS TOLERANCE OF PLANTS | BAYER CROPSCIENCE AG (DE) | 2015-04-09 | — | — | WO | disclosed |
| CN-102459202-A | Isoxazolines as inhibitors of fatty acid amide hydrolase | INFINITY PHARMACEUTICALS INC | 2012-05-16 | — | — | CN | disclosed |