Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29970861 | 0.94 | CYP1A2 (0.41) | CYP1A2GPR35ALDH1A1CA12CA1 | |
| SCHEMBL26131807 | 0.94 | CYP1A2 (0.41) | CYP1A2GPR35ALDH1A1CA12CA1 | |
| SCHEMBL16619269 | 0.85 | CYP1A2 (0.42) | CYP1A2GPR35ALDH1A1MAPTMEN1 | |
| SCHEMBL21136934 | 0.83 | MAPT (0.41) | GPR35ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL21099305 | 0.83 | MAPT (0.41) | GPR35ALDH1A1CA12CA1CA2 | |
| SCHEMBL15973592 | 0.82 | PDGFRB (0.40) | MAPTKDM4EMEN1KMT2APOLB | |
| SCHEMBL16470135 | 0.80 | MAPT (0.41) | CYP1A2GPR35ALDH1A1CA12CA1 | |
| SCHEMBL26131542 | 0.80 | PDGFRB (0.43) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL29970057 | 0.80 | PDGFRB (0.43) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL16618995 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |