Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | GALR2 | O43603 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618995 | 0.88 | ALDH1A1 (0.46) | ALDH1A1POLBLMNASMN1; SMN2HPGD | |
| SCHEMBL16619278 | 0.81 | MAPT (0.36) | ALDH1A1POLBLMNAKMT2AMEN1 | |
| SCHEMBL26131871 | 0.76 | CYP1A2 (0.37) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL29969235 | 0.76 | CYP1A2 (0.37) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL21050767 | 0.75 | MAPT (0.37) | ALDH1A1LMNASMN1; SMN2HPGDHSP90AA1 | |
| SCHEMBL31092311 | 0.74 | ALDH1A1 (0.52) | ALDH1A1POLBLMNASMN1; SMN2HPGD | |
| SCHEMBL3125659 | 0.74 | ALDH1A1 (0.52) | ALDH1A1POLBLMNASMN1; SMN2HPGD | |
| SCHEMBL2910396 | 0.74 | MAPT (0.50) | ALDH1A1NPSR1KMT2AMEN1MAPT | |
| SCHEMBL21201268 | 0.74 | NUDT1 (0.46) | ALDH1A1POLBSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL2913920 | 0.74 | MAPT (0.56) | ALDH1A1LMNANPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |