Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 2/20 | 0.46 |
| ▸ | GALR2 | O43603 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618900 | 0.88 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2POLBHPGDNPSR1 | |
| SCHEMBL16618924 | 0.81 | MAPT (0.36) | ALDH1A1SMN1; SMN2POLBHPGDNPSR1 | |
| SCHEMBL16618826 | 0.79 | CYP1A2 (0.41) | ALDH1A1POLBMAPTGAAKMT2A | |
| SCHEMBL23577809 | 0.76 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2POLBHPGDNPSR1 | |
| SCHEMBL29970861 | 0.76 | CYP1A2 (0.41) | ALDH1A1POLBMAPTGAAKMT2A | |
| SCHEMBL26131807 | 0.76 | CYP1A2 (0.41) | ALDH1A1POLBMAPTGAAKMT2A | |
| SCHEMBL15973592 | 0.76 | PDGFRB (0.40) | POLBLMNAMAPTKMT2AMEN1 | |
| SCHEMBL7573464 | 0.76 | MAPT (0.49) | ALDH1A1SMN1; SMN2NPSR1MAPK1MAPT | |
| SCHEMBL16619308 | 0.75 | PDGFRB (0.43) | ALDH1A1POLBHPGDLMNAMAPK1 | |
| SCHEMBL15054272 | 0.75 | MAPK1 (0.45) | ALDH1A1SMN1; SMN2HPGDNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |