SCHEMBL16619131

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12407008	0.88	ATM (0.47)	ATMCYP11B1CYP11B2CYP2A6ALDH1A1
	SCHEMBL16630310	0.86	KDM4E (0.43)	HTR2CSLC6A4GLSCACNA1GCACNA1B
	SCHEMBL2618862	0.85	KDM4E (0.40)	HTR2CSLC6A4GLSCACNA1GCACNA1B
	SCHEMBL17660859	0.82	CLK1 (0.42)	CYP11B1CYP11B2HTR2CSLC6A4GLS
	SCHEMBL21278439	0.81	HTR2C (0.39)	HTR2CSLC6A4GLSCACNA1GCACNA1B
	SCHEMBL16629762	0.81	HTR2C (0.41)	CYP11B1CYP11B2HTR2CSLC6A4GLS
	SCHEMBL16947896	0.81	HTR2C (0.41)	HTR2CSLC6A4GLSCACNA1GCACNA1B
	SCHEMBL18017408	0.81	HTR2C (0.41)	ATMHTR2CSLC6A4GLSCACNA1G
	SCHEMBL16629765	0.81	HTR2C (0.39)	HTR2CSLC6A4GLSCACNA1GCACNA1B
	SCHEMBL1830055	0.81	LOXL2 (0.54)	HTR2CSLC6A4GLSALDH1A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.