SCHEMBL16619429

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10859843	0.86	PDCD1 (0.53)	PDCD1CD274SMN1; SMN2
	SCHEMBL1420648	0.84	CYP1A2 (0.62)	CYP1A2CYP2D6CYP2C19TAAR1SMN1; SMN2
	SCHEMBL5275606	0.81	CYP1A2 (0.66)	CYP1A2CYP2D6CYP2C19TAAR1
	SCHEMBL6183546	0.81	CYP1A2 (0.76)	CYP1A2CYP2D6CYP2C19TAAR1KDM4E
	SCHEMBL19524534	0.80	GAA (0.63)	CYP1A2CYP2D6CYP2C19TAAR1
	SCHEMBL31393518	0.80	FFAR1 (0.59)	CYP1A2CYP2D6CYP2C19KDM4EMTOR
	SCHEMBL2670053	0.79	SLC2A4 (0.59)	CYP1A2PDCD1CD274SMN1; SMN2KDM4E
	SCHEMBL19633152	0.79	CYP1A2 (0.88)	CYP1A2CYP2D6CYP2C19TAAR1SMN1; SMN2
	SCHEMBL3360339	0.79	CYP1A2 (0.57)	CYP1A2CYP2D6CYP2C19TAAR1KDM4E
	SCHEMBL24257042	0.78	CYP1A2 (0.57)	CYP1A2CYP2D6CYP2C19TAAR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.