Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | S100A4 | P26447 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | EIF4E | P06730 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30991376 | 0.74 | ALDH1A1 (0.58) | ALDH1A1TDP1L3MBTL1S100A4PTPRC | |
| SCHEMBL13982693 | 0.74 | ALDH1A1 (0.58) | ALDH1A1TDP1L3MBTL1S100A4PTPRC | |
| SCHEMBL4091954 | 0.74 | HTR7 (0.47) | ALDH1A1TDP1L3MBTL1MAPK1APP | |
| SCHEMBL11502537 | 0.74 | ALDH1A1 (0.46) | ALDH1A1TDP1L3MBTL1S100A4PTPRC | |
| SCHEMBL6425266 | 0.74 | ALDH1A1 (0.72) | ALDH1A1TDP1L3MBTL1S100A4PTPRC | |
| SCHEMBL1554959 | 0.74 | TDP1 (0.52) | ALDH1A1TDP1L3MBTL1MAPK1NPC1 | |
| SCHEMBL1355833 | 0.72 | ALDH1A1 (0.42) | ALDH1A1TDP1L3MBTL1MAPK1NPC1 | |
| SCHEMBL13133450 | 0.71 | TSHR (0.56) | ALDH1A1TDP1L3MBTL1S100A4PTPRC | |
| SCHEMBL10887956 | 0.70 | HTT (0.45) | ALDH1A1TDP1L3MBTL1MAPK1NPC1 | |
| SCHEMBL6690612 | 0.70 | ALDH1A1 (0.53) | ALDH1A1TDP1L3MBTL1S100A4PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052520-A2 | STABILIZED POLYPEPTIDES AND USES THEREOF | President and Fellows of Harvard College (US) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015051030-A2 | STABILIZED POLYPEPTIDES AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-04-09 | — | — | WO | disclosed |