Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11502537 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MAPK1KMT2AMAPTLMNA | |
| SCHEMBL10904423 | 0.77 | VCAM1 (0.42) | NPC1MERTKMAPTFBP1 | |
| SCHEMBL6191715 | 0.75 | HTR7 (0.44) | HTR7APPSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1355833 | 0.74 | ALDH1A1 (0.42) | HTR7ALDH1A1MAPK1SMN1; SMN2NPC1 | |
| SCHEMBL16619607 | 0.74 | ALDH1A1 (0.51) | APPALDH1A1MAPK1SMN1; SMN2NPC1 | |
| SCHEMBL30564539 | 0.72 | HTR7 (0.48) | HTR7APPALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL3538557 | 0.70 | APP (0.44) | HTR7APPALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8310372 | 0.70 | ALDH1A1 (0.42) | ALDH1A1MAPK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27530428 | 0.70 | ERN1 (0.49) | HTR7APPALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL27530426 | 0.70 | SMN1; SMN2 (0.53) | HTR7APPALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009078813-A1 | METHOD OF FORMING OSELTAMIVIR AND DERIVATIVES THEREOF | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2009-06-25 | — | — | WO | disclosed |