SCHEMBL16619619

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13884135	0.85	L3MBTL1 (0.38)	TAAR1SLC18A2SIGMAR1L3MBTL1AURKA
	SCHEMBL16619580	0.77	HCAR2 (0.32)	L3MBTL1CYP2D6CYP2C19
	SCHEMBL16629867	0.76	TAAR1 (0.42)	TAAR1SLC18A2SIGMAR1L3MBTL1CYP2D6
	SCHEMBL9322413	0.71	KDM4E (0.51)	TAAR1SLC18A2SIGMAR1L3MBTL1CYP2D6
	SCHEMBL21914932	0.70	PTPRB (0.47)	TAAR1SLC18A2SIGMAR1L3MBTL1CYP2D6
	SCHEMBL1541692	0.69	TAAR1 (0.57)	TAAR1SLC18A2SIGMAR1L3MBTL1CYP2D6
	SCHEMBL13621464	0.69	TAAR1 (0.57)	TAAR1SLC18A2SIGMAR1L3MBTL1CYP2D6
	SCHEMBL13621571	0.69	TAAR1 (0.57)	TAAR1SLC18A2SIGMAR1L3MBTL1CYP2D6
	SCHEMBL16199253	0.69	TAAR1 (0.44)	TAAR1SLC18A2SIGMAR1L3MBTL1CYP2D6
	SCHEMBL7505281	0.69	TAAR1 (0.44)	TAAR1SLC18A2SIGMAR1L3MBTL1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.