SCHEMBL16619998

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16626941	0.83	P2RX7 (0.56)	KDM1ARXRAGRIN1GRIN2B
	SCHEMBL16626930	0.83	NOTUM (0.47)	RXRAGRIN1GRIN2B
	SCHEMBL16626927	0.80	RXRA (0.47)	ALDH1A1CHRNA7RXRAGRIN1GRIN2B
	SCHEMBL16620124	0.76	HSP90AB1 (0.61)	KMT2A
	SCHEMBL16626917	0.75	HSP90AB1 (0.51)	ALDH1A1KDM1A
	SCHEMBL15211851	0.73	MAPT (0.54)	ALDH1A1SYKCHRNA7
	SCHEMBL15211924	0.73	MAPT (0.54)	ALDH1A1SYKCHRNA7
	SCHEMBL16626921	0.72	HSP90AB1 (0.54)	ALDH1A1
	SCHEMBL19889344	0.72	RXRA (0.59)	RXRAGRIN1GRIN2B
	SCHEMBL18028296	0.72	HSP90AB1 (0.47)	ALDH1A1KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.