SCHEMBL16626927

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16626917	0.83	HSP90AB1 (0.51)	KDM4EALDH1A1SMN1; SMN2POLB
	SCHEMBL16626941	0.82	P2RX7 (0.56)	RXRAGRIN1GRIN2B
	SCHEMBL16626930	0.80	NOTUM (0.47)	RXRAGRIN1GRIN2BKDM4E
	SCHEMBL16619998	0.80	ALDH1A1 (0.48)	RXRAGRIN1GRIN2BALDH1A1CHRNA7
	SCHEMBL19889344	0.78	RXRA (0.59)	RXRAGRIN1GRIN2BSMN1; SMN2POLB
	SCHEMBL18028296	0.78	HSP90AB1 (0.47)	KDM4EALDH1A1SMN1; SMN2
	SCHEMBL19876881	0.76	TDP1 (0.46)	RXRAGRIN1GRIN2BKDM4ESMN1; SMN2
	SCHEMBL24336729	0.76	MAPT (0.46)	RXRAGRIN1GRIN2BSMN1; SMN2MAPT
	SCHEMBL6712868	0.74	KDM4E (0.61)	KDM4EALDH1A1SMN1; SMN2POLBPKM
	SCHEMBL21365233	0.74	MIF (0.45)	RXRAGRIN1GRIN2BPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.