Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UMPS | P11172 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CDA | P32320 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 6/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | PYGL | P06737 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489385 | 0.79 | PYGL (0.50) | MAPTHIF1APYGLKDM4EGMNN | |
| SCHEMBL4193972 | 0.79 | PYGL (0.50) | MAPTHIF1APYGLKDM4EGMNN | |
| SCHEMBL11284980 | 0.79 | PYGL (0.50) | MAPTHIF1APYGLKDM4EGMNN | |
| Phosphoric Acid SCHEMBL30522657 | 0.76 | PYGL (0.45) | MAPTCDAHIF1APYGLKDM4E | |
| SCHEMBL25392367 | 0.76 | PYGM (0.41) | MAPTCDAPNPPYGL | |
| SCHEMBL26235861 | 0.76 | PYGM (0.41) | MAPTCDAPNPPYGL | |
| SCHEMBL6790218 | 0.74 | HIF1A (0.43) | UMPSMAPTCDAHIF1APYGL | |
| SCHEMBL6790225 | 0.74 | HIF1A (0.43) | UMPSMAPTCDAHIF1APYGL | |
| SCHEMBL1998975 | 0.74 | SLC5A2 (0.40) | PNPPYGL | |
| SCHEMBL9293545 | 0.74 | SLC5A2 (0.40) | PNPPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052479-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | Moderna Therapeutics, Inc. (US) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |