SCHEMBL1998975

SCHEMBL1998975

O=c1[nH]cccc1C1O[C@H](CO)[C@H](O)[C@H]1O

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 7/20 0.40
PNP P00491 5/20 0.40
ALDH1A1 P00352 1/20 0.40
PYGL P06737 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9293545 1.00 SLC5A2 (0.40) SLC5A2PNPALDH1A1PYGL
SCHEMBL1022027 1.00 SLC5A2 (0.40) SLC5A2PNPALDH1A1PYGL
SCHEMBL16620686 1.00 SLC5A2 (0.40) SLC5A2PNPALDH1A1PYGL
SCHEMBL4293687 0.77 KDM4E (0.49) SLC5A2PNPALDH1A1
SCHEMBL24420223 0.75 TK1 (0.39)
SCHEMBL1996325 0.75 PNP (0.43) SLC5A2PNP
SCHEMBL1675551 0.75 TK1 (0.39)
SCHEMBL18080095 0.75 PYGL (0.43) SLC5A2PYGL
SCHEMBL17329460 0.75 PNP (0.44) SLC5A2PNPPYGL
SCHEMBL21847661 0.75 PNP (0.44) SLC5A2PNPPYGL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7960543-B2 Nucleoside or nucleotide derivative and use thereof RIKEN (JP) 2011-06-14 US disclosed
US-20090275017-A1 Novel Nucleoside or Nucleotide Derivative and Use Thereof RIKEN (JP) 2009-11-05 US disclosed
EP-1816130-A1 NOVEL NUCLEOSIDE OR NUCLEOTIDE DERIVATIVE AND USE THEREOF Riken (JP) 2007-08-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090275017-A1 Novel Nucleoside or Nucleotide Derivative and Use Thereof DUT, NT5C3B, NT5C SLC5A2 1291/4885PNP 52/4885ALDH1A1 2280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.