Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CDA | P32320 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.38 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ribose (Furanose) SCHEMBL346135 | 0.77 | LMNA (0.49) | PNPALDH1A1GMNNLMNATP53 | |
| Ribose (Furanose) SCHEMBL10787751 | 0.77 | LMNA (0.49) | PNPALDH1A1GMNNLMNATP53 | |
| Xanthine SCHEMBL11134143 | 0.77 | ACHE (0.59) | PNPCDAMAPTSLC28A1SLC28A2 | |
| Xanthine SCHEMBL133793 | 0.77 | ACHE (0.59) | PNPCDAMAPTSLC28A1SLC28A2 | |
| Hypoxanthine SCHEMBL9538156 | 0.77 | ALDH1A1 (0.53) | PNPALDH1A1CDAMAPTMEN1 | |
| Ribose (Furanose) SCHEMBL5526657 | 0.75 | CRBN (0.52) | ALDH1A1SLC28A1SLC28A2SLC29A1SLC28A3 | |
| Ribose (Furanose) SCHEMBL16337481 | 0.75 | CRBN (0.52) | ALDH1A1SLC28A1SLC28A2SLC29A1SLC28A3 | |
| Ribose (Furanose) SCHEMBL4632749 | 0.75 | CRBN (0.52) | ALDH1A1SLC28A1SLC28A2SLC29A1SLC28A3 | |
| Ribose (Furanose) SCHEMBL2751838 | 0.75 | CRBN (0.52) | ALDH1A1SLC28A1SLC28A2SLC29A1SLC28A3 | |
| Ribose (Furanose) SCHEMBL9621710 | 0.74 | SLC5A2 (0.39) | ALDH1A1SLC28A1SLC28A2SLC29A1SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052479-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | Moderna Therapeutics, Inc. (US) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |