Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.64 |
| ▸ | CASP3 | P42574 | 2/20 | 0.60 |
| ▸ | CASP7 | P55210 | 1/20 | 0.60 |
| ▸ | TACR1 | P25103 | 2/20 | 0.56 |
| ▸ | CASP1 | P29466 | 2/20 | 0.55 |
| ▸ | CASP9 | P55211 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 2/20 | 0.55 |
| ▸ | CTSS | P25774 | 2/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | APC | P25054 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1660344 | 1.00 | CTSL (0.64) | CTSLCASP3CASP7TACR1CASP1 | |
| SCHEMBL1661924 | 0.94 | CTSL (0.71) | CTSLTACR1CTSBCTSSCTSK | |
| SCHEMBL1663171 | 0.94 | CTSL (0.71) | CTSLTACR1CTSBCTSSCTSK | |
| SCHEMBL1661910 | 0.92 | CTSL (0.65) | CTSLCASP3CASP7TACR1CASP1 | |
| SCHEMBL1661176 | 0.92 | CTSL (0.65) | CTSLCASP3CASP7TACR1CASP1 | |
| SCHEMBL1661020 | 0.89 | CTSL (0.53) | CTSLCASP3CASP7TACR1CASP1 | |
| SCHEMBL6370513 | 0.88 | CTSL (0.63) | CTSLTACR1CASP1CTSBCTSS | |
| SCHEMBL9862186 | 0.88 | CASP3 (0.61) | CTSLCASP3CASP7TACR1CASP1 | |
| SCHEMBL6378208 | 0.86 | CTSL (0.72) | CTSLTACR1CTSBCTSSCTSK | |
| SCHEMBL21786578 | 0.86 | PTPN1 (0.66) | CTSLCTSBCTSSCTSKPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | claimed |
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | disclosed |