Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.63 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | CTSB | P07858 | 5/20 | 0.56 |
| ▸ | CTSS | P25774 | 2/20 | 0.56 |
| ▸ | CTSK | P43235 | 2/20 | 0.56 |
| ▸ | REN | P00797 | 2/20 | 0.56 |
| ▸ | APC | P25054 | 1/20 | 0.55 |
| ▸ | TACR1 | P25103 | 2/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1661924 | 0.93 | CTSL (0.71) | CTSLCAPN1CTSBCTSSCTSK | |
| SCHEMBL1663171 | 0.93 | CTSL (0.71) | CTSLCAPN1CTSBCTSSCTSK | |
| SCHEMBL6371162 | 0.91 | CASP1 (0.61) | CTSLCAPN1CASP1CTSBCTSS | |
| SCHEMBL21786578 | 0.89 | PTPN1 (0.66) | CTSLCAPN1CTSBCTSSCTSK | |
| SCHEMBL10971243 | 0.89 | CAPN1 (0.67) | CTSLCAPN1CTSBCTSSCTSK | |
| SCHEMBL1662038 | 0.88 | CTSL (0.64) | CTSLCASP1CTSBCTSSCTSK | |
| SCHEMBL1660344 | 0.88 | CTSL (0.64) | CTSLCASP1CTSBCTSSCTSK | |
| SCHEMBL10968600 | 0.88 | CTSL (0.61) | CTSLCAPN1CASP1CTSBCTSS | |
| SCHEMBL10972180 | 0.88 | CTSL (0.61) | CTSLCAPN1CASP1CTSBCTSS | |
| SCHEMBL7204154 | 0.88 | CAPN1 (0.67) | CTSLCAPN1CASP1CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6960559-B1 | Neurite growth regulatory factors | UNIVERSITY OF ZURICH (CH) | 2005-11-01 | — | — | US | disclosed |
| US-5250414-A | Metalloendoprotease cleavage of tetrapeptide | ERZIEHUNGSDIREKTION OF THE CANTON ZURICH (CH) | 1993-10-05 | — | — | US | disclosed |
| WO-1993000427-A2 | NEURITE GROWTH REGULATORY FACTORS | ERZIEHUNGSDIREKTION OF THE CANTON ZURICH (CH) | 1993-01-07 | — | — | WO | disclosed |