Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.61 |
| ▸ | TOP1 | P11387 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | FAAH | O00519 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | APEX1 | P27695 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16620762 | 1.00 | HRH3 (0.61) | HRH3TOP1MAPTBLMHSD17B10 | |
| SCHEMBL16620111 | 0.97 | HRH3 (0.66) | HRH3TOP1MAPTBLMHSD17B10 | |
| SCHEMBL16620112 | 0.97 | HRH3 (0.66) | HRH3TOP1MAPTBLMHSD17B10 | |
| SCHEMBL3233808 | 0.94 | MEN1 (0.62) | MAPTBLMHSD17B10FAAHUSP2 | |
| SCHEMBL3233804 | 0.94 | MEN1 (0.62) | MAPTBLMHSD17B10FAAHUSP2 | |
| SCHEMBL16626967 | 0.93 | MEN1 (0.63) | HRH3MAPTBLMHSD17B10ALOX15 | |
| SCHEMBL16620081 | 0.87 | HSP90AA1 (0.53) | HRH3HSD17B10FAAHALOX15KMT2A | |
| SCHEMBL8513443 | 0.87 | HSP90AA1 (0.53) | HRH3HSD17B10FAAHALOX15KMT2A | |
| SCHEMBL3230247 | 0.87 | HSP90AA1 (0.53) | HRH3HSD17B10FAAHALOX15KMT2A | |
| SCHEMBL8511093 | 0.85 | HSP90AA1 (0.52) | HRH3HSD17B10FAAHALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11122826-B2 | Organic compounds | GIVAUDAN SA (CH) | 2021-09-21 | — | — | US | claimed |
| US-10660355-B2 | — | — | 2020-05-26 | — | — | US | claimed |
| EP-3052472-A1 | N-ACYLATED 2-AMINOISOBUTYRIC ACID COMPOUNDS AND FLAVOUR COMPOSITIONS CONTAINING THEM | Givaudan S.A. (CH) | 2016-08-10 | — | — | EP | claimed |
| US-20160213038-A1 | Improvements in or Relating to Organic Compounds | GIVAUDAN S.A. (CH) | 2016-07-28 | — | — | US | claimed |
| WO-2015050536-A1 | N-ACYLATED 2-AMINOISOBUTYRIC ACID COMPOUNDS AND FLAVOUR COMPOSITIONS CONTAINING THEM | GIVAUDAN S.A. (CH) | 2015-04-09 | — | — | WO | claimed |
| US-11122826-B2 | Organic compounds | GIVAUDAN SA (CH) | 2021-09-21 | — | — | US | disclosed |
| US-10660355-B2 | — | — | 2020-05-26 | — | — | US | disclosed |
| EP-3052472-A1 | N-ACYLATED 2-AMINOISOBUTYRIC ACID COMPOUNDS AND FLAVOUR COMPOSITIONS CONTAINING THEM | Givaudan S.A. (CH) | 2016-08-10 | — | — | EP | disclosed |
| US-20160213038-A1 | Improvements in or Relating to Organic Compounds | GIVAUDAN S.A. (CH) | 2016-07-28 | — | — | US | disclosed |
| WO-2015050536-A1 | N-ACYLATED 2-AMINOISOBUTYRIC ACID COMPOUNDS AND FLAVOUR COMPOSITIONS CONTAINING THEM | GIVAUDAN S.A. (CH) | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10660355-B2 | — | TAS2R5, TAS2R10, TAS2R1 | HRH3 1286/4885TOP1 4704/4885MAPT 3002/4885 |
| US-11122826-B2 | Organic compounds | TAS2R1, TAS2R5, TAS2R10 | HRH3 1434/4885TOP1 4656/4885MAPT 1688/4885 |
| US-20160213038-A1 | Improvements in or Relating to Organic Compounds | TAS2R38, TAS2R1, TAS2R5 | HRH3 1604/4885TOP1 4647/4885MAPT 1708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.