Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.49 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.48 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.48 |
| ▸ | GNPAT | O15228 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | CPA2 | P48052 | 1/20 | 0.46 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.45 |
| ▸ | PAM | P19021 | 1/20 | 0.45 |
| ▸ | CCKAR | P32238 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1661066 | 0.90 | AVPR1A (0.44) | NMUR2NMUR1AVPR1ANAALAD2CCKAR | |
| SCHEMBL1662059 | 0.89 | CTSL (0.54) | — | |
| SCHEMBL1661011 | 0.88 | ACE (0.48) | BACE1BACE2NMUR2NMUR1AVPR1A | |
| SCHEMBL12794620 | 0.86 | NPY4R (0.54) | GNPAT | |
| SCHEMBL12792613 | 0.86 | NPY4R (0.54) | GNPAT | |
| SCHEMBL1663151 | 0.85 | CTSL (0.44) | BACE1NMUR2NMUR1AVPR1ANAALAD2 | |
| SCHEMBL1661229 | 0.83 | ACE (0.51) | BACE1BACE2AVPR1ANAALAD2OPRM1 | |
| SCHEMBL13563442 | 0.80 | ACE (0.60) | GNPAT | |
| SCHEMBL13563439 | 0.80 | ACE (0.60) | GNPAT | |
| SCHEMBL13563434 | 0.80 | ACE (0.60) | GNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | claimed |
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | disclosed |