Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663148 | 0.90 | APC (0.51) | ACEAVPR1ANAALAD2BACE1BACE2 | |
| SCHEMBL1661066 | 0.89 | AVPR1A (0.44) | ACEAVPR1ANAALAD2 | |
| SCHEMBL12793611 | 0.85 | NPY4R (0.60) | — | |
| SCHEMBL1661011 | 0.83 | ACE (0.48) | ACEAVPR1ABACE1BACE2OPRM1 | |
| SCHEMBL1662080 | 0.83 | BACE1 (0.49) | AVPR1ANAALAD2BACE1BACE2OPRM1 | |
| SCHEMBL25676454 | 0.80 | ACE (0.57) | ACE | |
| SCHEMBL1663151 | 0.79 | CTSL (0.44) | AVPR1ANAALAD2BACE1 | |
| SCHEMBL1661176 | 0.79 | CTSL (0.65) | — | |
| SCHEMBL1661910 | 0.79 | CTSL (0.65) | — | |
| SCHEMBL1660926 | 0.79 | CTSL (0.56) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | claimed |
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | disclosed |