Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | APC | P25054 | 3/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP9 | P55211 | 1/20 | 0.42 |
| ▸ | CCKAR | P32238 | 4/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.41 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 2/20 | 0.41 |
| ▸ | CCKBR | P32239 | 3/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19252727 | 0.94 | FOLH1 (0.47) | CTSLCTSBCTSSCTSKAPC | |
| SCHEMBL1663148 | 0.90 | APC (0.51) | CTSLCTSBCTSSCTSKAPC | |
| SCHEMBL1661066 | 0.90 | AVPR1A (0.44) | AVPR1ACCKARNAALAD2NMUR2NMUR1 | |
| SCHEMBL1662059 | 0.89 | CTSL (0.54) | CTSLCTSBCTSSCTSKAPC | |
| SCHEMBL1662080 | 0.85 | BACE1 (0.49) | AVPR1ACCKARNAALAD2NMUR2NMUR1 | |
| SCHEMBL1660926 | 0.83 | CTSL (0.56) | CTSLCTSBCTSSCTSKAPC | |
| SCHEMBL1661229 | 0.79 | ACE (0.51) | AVPR1ANAALAD2BACE1 | |
| SCHEMBL1661011 | 0.79 | ACE (0.48) | AVPR1ANMUR2NMUR1TACR3BACE1 | |
| SCHEMBL1661328 | 0.78 | NPY4R (0.37) | CTSLCTSBCTSSCTSKCCKAR | |
| SCHEMBL13731613 | 0.77 | NAALAD2 (0.40) | CTSLCTSBCTSSCTSKAPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | claimed |
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | disclosed |