Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 3/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15256053 | 0.87 | TOP1 (0.44) | MAOBPARP1TOP1KIF11TRPV1 | |
| SCHEMBL16622238 | 0.85 | NR3C1 (0.43) | MAOBALOX5APFEN1NPC1PDGFRB | |
| SCHEMBL15256076 | 0.84 | NPC1 (0.41) | ALOX5APFEN1NPC1PDGFRBKDR | |
| SCHEMBL16622240 | 0.84 | RAB9A (0.47) | ALOX5APFEN1NPC1PDGFRBKDR | |
| SCHEMBL15256055 | 0.84 | RAB9A (0.50) | NPC1PDGFRBKDRFLT3RAB9A | |
| SCHEMBL16949242 | 0.81 | ALOX5AP (0.37) | ALOX5APFEN1NPC1PDGFRBKDR | |
| SCHEMBL16949235 | 0.80 | NR1H4 (0.49) | MAOBPARP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13072034 | 0.79 | ALOX5AP (0.42) | ALOX5APFEN1NPC1PDGFRBKDR | |
| SCHEMBL15256061 | 0.78 | RAC1 (0.43) | MAOBALOX5APFEN1NPC1PDGFRB | |
| SCHEMBL16622278 | 0.77 | KIF11 (0.46) | MAOBTOP1KIF11TRPV1TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8999520-B2 | Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-04-07 | — | — | US | disclosed |