SCHEMBL16622245

SCHEMBL16622245

Cc1cccc(-c2ccccc2)c1-c1ncc(-c2ccccc2)nc1-c1ccccc1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
NPC1 O15118 1/20 0.44
PDGFRB P09619 1/20 0.44
KDR P35968 1/20 0.44
FLT3 P36888 1/20 0.44
ATR Q13535 7/20 0.41
ENPP3 O14638 1/20 0.40
ENPP1 P22413 1/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
POLB P06746 1/20 0.40
PKM P14618 1/20 0.40
KMT2A Q03164 1/20 0.40
ADORA2A P29274 3/20 0.36
ADORA1 P30542 3/20 0.36
TLR9 Q9NR96 1/20 0.36
GLA P06280 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28019522 0.82 RAB9A (0.51) RAB9ASMN1; SMN2NPC1PDGFRBKDR
SCHEMBL13071592 0.80 ALDH1A1 (0.50) RAB9ASMN1; SMN2NPC1PDGFRBKDR
SCHEMBL16622237 0.79 ATR (0.46) RAB9ASMN1; SMN2NPC1PDGFRBKDR
SCHEMBL12854146 0.77 ATR (0.40) RAB9ASMN1; SMN2NPC1PDGFRBKDR
SCHEMBL16622230 0.77 ADORA2A (0.41) RAB9ANPC1ENPP3ENPP1ALDH1A1
SCHEMBL16622247 0.76 ALDH1A1 (0.46) RAB9ASMN1; SMN2NPC1PDGFRBKDR
SCHEMBL16738287 0.75 CKS1B (0.49) RAB9ASMN1; SMN2NPC1PDGFRBKDR
SCHEMBL16622257 0.75 ATR (0.47) RAB9ASMN1; SMN2NPC1PDGFRBKDR
SCHEMBL16948795 0.75 RAB9A (0.47) RAB9ASMN1; SMN2NPC1PDGFRBKDR
SCHEMBL15256055 0.74 RAB9A (0.50) RAB9ASMN1; SMN2NPC1PDGFRBKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150214484-A1 Organometallic Complex and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Organometallic Complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-07-30 US disclosed
US-8999520-B2 Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-04-07 US disclosed