SCHEMBL16622248

SCHEMBL16622248

COc1ccc(-c2nc(-c3ccccc3)cnc2-c2ccc(OC)cc2C)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.50
ALDH1A1 P00352 3/20 0.50
KDM4E B2RXH2 2/20 0.50
LMNA P02545 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
NPC1 O15118 6/20 0.49
RAB9A P51151 6/20 0.49
ACACA Q13085 1/20 0.47
CASP3 P42574 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
MAPK1 P28482 1/20 0.44
RECQL P46063 1/20 0.44
MAPT P10636 2/20 0.44
DYRK1A Q13627 1/20 0.44
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
GLA P06280 1/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15256099 0.90 NPC1 (0.49) ALDH1A1KDM4ENPC1RAB9AACACA
SCHEMBL16622277 0.85 NPC1 (0.46) L3MBTL1ALDH1A1KDM4ELMNATDP1
SCHEMBL16622250 0.84 NPC1 (0.41) L3MBTL1ALDH1A1KDM4ENPC1RAB9A
SCHEMBL16949227 0.84 RAB9A (0.49) L3MBTL1ALDH1A1KDM4ETDP1NPC1
SCHEMBL15256043 0.82 TDP1 (0.47) L3MBTL1ALDH1A1KDM4ENPSR1TDP1
SCHEMBL15256079 0.81 TDP1 (0.46) L3MBTL1ALDH1A1KDM4ENPSR1TDP1
SCHEMBL14307063 0.81 KDM4E (0.54) L3MBTL1ALDH1A1KDM4ELMNANPSR1
SCHEMBL16622233 0.79 RAB9A (0.43) ALDH1A1KDM4ETDP1NPC1RAB9A
SCHEMBL16622246 0.79 RAB9A (0.43) ALDH1A1KDM4ETDP1NPC1RAB9A
SCHEMBL16948795 0.78 RAB9A (0.47) L3MBTL1ALDH1A1KDM4ETDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8999520-B2 Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-04-07 US disclosed