Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15256099 | 0.85 | NPC1 (0.49) | NPC1RAB9ACYP11B1CYP11B2CYP1A2 | |
| SCHEMBL16622248 | 0.85 | L3MBTL1 (0.50) | NPC1RAB9AFLT3CYP11B1CYP11B2 | |
| SCHEMBL15256049 | 0.82 | CA12 (0.41) | NPC1RAB9AFLT3CYP1A2CYP3A4 | |
| SCHEMBL16622250 | 0.80 | NPC1 (0.41) | NPC1RAB9AACACACRHR1CASP3 | |
| SCHEMBL16622247 | 0.80 | ALDH1A1 (0.46) | NPC1RAB9AFLT3CYP1A2CYP17A1 | |
| SCHEMBL12989388 | 0.76 | CYP11B1 (0.52) | RAB9ACYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL16949235 | 0.74 | NR1H4 (0.49) | NPC1RAB9AACACACASP3SENP7 | |
| SCHEMBL12320582 | 0.73 | CRHR1 (0.50) | CYP11B1CYP11B2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15256072 | 0.72 | NPC1 (0.55) | NPC1RAB9ACYP11B1CYP11B2CYP1A2 | |
| SCHEMBL16622237 | 0.72 | ATR (0.46) | NPC1RAB9AFLT3MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8999520-B2 | Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-04-07 | — | — | US | disclosed |