Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16948819 | 0.91 | NPC1 (0.41) | NPC1RAB9APDK2MAPTCASP3 | |
| SCHEMBL15256047 | 0.85 | RAB9A (0.44) | NPC1RAB9APDK2MAPTPKM | |
| SCHEMBL15256099 | 0.85 | NPC1 (0.49) | NPC1RAB9AMAPTCASP3SENP7 | |
| SCHEMBL16622248 | 0.84 | L3MBTL1 (0.50) | NPC1RAB9AMAPTCASP3SENP7 | |
| SCHEMBL13212326 | 0.83 | PDK2 (0.37) | NPC1RAB9APDK2MAPTCASP3 | |
| SCHEMBL15256048 | 0.83 | RAB9A (0.42) | NPC1RAB9APDK2MAPTPKM | |
| SCHEMBL13072032 | 0.80 | RAB9A (0.41) | NPC1RAB9APDK2MAPTPKM | |
| SCHEMBL16622277 | 0.80 | NPC1 (0.46) | NPC1RAB9AMAPTCASP3SENP7 | |
| SCHEMBL16622235 | 0.79 | PDK2 (0.37) | NPC1RAB9APDK2SMN1; SMN2ABL1 | |
| SCHEMBL14184269 | 0.76 | PDK2 (0.47) | NPC1RAB9APDK2MAPTMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8999520-B2 | Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2015-04-07 | — | — | US | disclosed |