SCHEMBL16622256

SCHEMBL16622256

COc1nc(-c2ccccc2)cnc1-c1ccccc1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SQOR Q9Y6N5 5/20 0.51
SMN1; SMN2 Q16637 4/20 0.46
MAPT P10636 4/20 0.46
ALDH1A1 P00352 4/20 0.46
GAA P10253 2/20 0.46
GLA P06280 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
PDGFRB P09619 1/20 0.45
KDR P35968 1/20 0.45
FLT3 P36888 1/20 0.45
KDM4E B2RXH2 3/20 0.43
HSD17B10 Q99714 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
HPGD P15428 1/20 0.43
MMP13 P45452 1/20 0.43
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28019522 0.83 RAB9A (0.51) SMN1; SMN2MAPTALDH1A1GAAGLA
SCHEMBL15256055 0.81 RAB9A (0.50) SMN1; SMN2MAPTALDH1A1GAAGLA
SCHEMBL16948795 0.79 RAB9A (0.47) SMN1; SMN2MAPTALDH1A1GAAGLA
SCHEMBL16622240 0.79 RAB9A (0.47) SMN1; SMN2MAPTALDH1A1GAAGLA
SCHEMBL29131667 0.77 SQOR (0.59) SQORSMN1; SMN2MAPTALDH1A1GAA
SCHEMBL30505741 0.77 SQOR (0.59) SQORSMN1; SMN2MAPTALDH1A1GAA
SCHEMBL16949235 0.77 NR1H4 (0.49) SMN1; SMN2MAPTALDH1A1GAANPC1
SCHEMBL15256058 0.77 TDP1 (0.50) SMN1; SMN2MAPTALDH1A1NPC1RAB9A
SCHEMBL10304956 0.76 SQOR (0.46) SQORSMN1; SMN2MAPTALDH1A1GAA
SCHEMBL15256054 0.75 ALDH1A1 (0.45) SMN1; SMN2MAPTALDH1A1GAAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150214484-A1 Organometallic Complex and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Organometallic Complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-07-30 US disclosed
US-8999520-B2 Organometallic complex and light emitting element, light emitting device, and electronic device using the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-04-07 US disclosed