Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.39 |
| ▸ | ACACA | Q13085 | 3/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.36 |
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9110377 | 0.86 | ACACA (0.45) | PARP10PARP15ACACAFFAR4ACACB | |
| SCHEMBL9114912 | 0.84 | ACACA (0.41) | ACACAFFAR4ACACBRIPK1 | |
| SCHEMBL9112880 | 0.83 | ACACB (0.46) | ACACAACACB | |
| SCHEMBL9110148 | 0.75 | ACACB (0.41) | ACACAACACBRIPK1 | |
| SCHEMBL9109737 | 0.74 | ACACB (0.47) | ACACAACACB | |
| SCHEMBL9113694 | 0.72 | PTGS2 (0.38) | FFAR4ACACBFFAR1 | |
| SCHEMBL9110509 | 0.72 | ACACB (0.42) | ACACAACACB | |
| SCHEMBL9114793 | 0.71 | ACACB (0.49) | ACACAACACB | |
| SCHEMBL9112867 | 0.71 | MTNR1A (0.46) | ACACAACACB | |
| SCHEMBL9113125 | 0.71 | ACACA (0.45) | PARP10PARP15ACACAACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649062-B1 | BICYCLIC COMPOUNDS AS INHIBITORS OF ACETYL-COA CARBOXYLASE (ACC) | TAKEDA PHARMACEUTICAL (JP) | 2015-04-08 | — | — | EP | disclosed |